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MetabolomicsDigital Phenomics and Dual-Fluid Metabolomics for Precision Stratification of Diabetic Kidney Disease: A Multicenter Cohort Study

We conducted a prospective-retrospective two-center cohort study involving 364 participants. The Discovery Cohort (n=282) enrolled from two centers consisted of healthy controls (n=80), patients with type 2 diabetes mellitus (T2DM) without kidney disease (n=102), and patients with confirmed DKD (...

2026-03-09 | MTBLS14007 | MetaboLights
ProteomicsProtein-based Cardiogenic Shock Patient Classifier
Cardiogenic shock (CS) is associated with high short-term mortality and a precise CS risk stratification could guide interventions to improve patient outcome. A 4-protein risk score (CS4P) was derived and validated for 90-day risk of mortality. The CS4P risk score, which comprises proteins Liver-fat...
ORGANISM(S): Homo Sapiens 
2021-01-24 | PXD011593 | panorama
TranscriptomicsImpact of Gene Expression Profiling Based Risk Stratification in Patients with Myeloma Receiving Initial Therapy with Lenalidomide and Dexamethasone
Detection of specific chromosomal abnormalities by FISH and metaphase cytogenetics allows risk stratification in multiple myeloma (MM); however, gene expression profiling (GEP) based signatures may enable more specific risk categorization. We examined the utility of two GEP-based risk stratification...
ORGANISM(S): Homo sapiens 
2011-08-25 | E-GEOD-31504 | biostudies-arrayexpress
TranscriptomicsLinking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia
GEP class prediction in association with CI-FISH (42 candidate genes) and patient MRD stratification Combined Interphase FISH (CI-FISH) for 42 candidate genes and Single Nucleotide Polymorphism (SNP) arrays were applied in a series of 51 T-ALL patients enrolled in Italy into the AIEOP-BFM ALL2000 pr...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-39816 | biostudies-arrayexpress
ProteomicsSpatial characterization and stratification of colorectal adenomas by Deep Visual Proteomics
Background and Aims: Colorectal adenomas (CRAs) are precursor lesions that can progress to adenocarcinomas. Current clinical guidelines categorize patients into risk groups based on adenoma characteristics observed during index colonoscopy, but this may lead to overtreatment. Our aim was to establis...
ORGANISM(S): Homo sapiens (Human) 
2024-08-04 | PXD046999 | Pride
Spatial Mass spectrometry Pathology Cancer Colorectal adenoma Proteomics Dvp 
GenomicsA novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma [Illumina]
A novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma [Illumina]
PRJNA670013 | ENA
GenomicsA novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma [Agilent]
A novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma [Agilent]
PRJNA669848 | ENA
ClinicalIdentification of New Patient Stratification Tools in MSS RAS mt mCRC
This is a translational, multicentre and multinational study. The aim of this study is to identify new patient stratification tools in microsatellite stable RAS mutant metastatic Colorectal Cancer
2286288 | ecrin-mdr-crc
GenomicsAn Integrated Approach to Patient Stratification and Therapy Selection in Acute Myeloid Leukemia
As more clinically-relevant genomic features of myeloid malignancies are revealed, it has become clear that targeted clinical genetic testing is inadequate for risk stratification. Here, we developed and validated a clinical transcriptome-based assay for stratification of acute myeloid leukemia (AML...
EGAS00001004655 | EGA
GenomicsDiscovery and Evaluation of Biomarkers for Triple-Negative Breast Cancer Subtypes Uncovers Patient Stratification and Targeted Therapeutic Strategies
Discovery and Evaluation of Biomarkers for Triple-Negative Breast Cancer Subtypes Uncovers Patient Stratification and Targeted Therapeutic Strategies
PRJNA1280172 | ENA
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