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ProteomicsA tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling
Pseudomonas aeruginosa is a difficult-to-treat Gram-negative bacterial pathogen causing life-threatening infections. Adaptive resistance (AR) to cationic peptide antibiotics such as polymyxin B impairs the therapeutic success. This self-protection is mediated by two component systems consisting of a...
ORGANISM(S): Pseudomonas Aeruginosa Pao1 
2021-08-19 | PXD022470 | panorama
ProteomicsFIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1.
The asparagine hydroxylase, factor inhibiting HIF (FIH) confers oxygen-dependence upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hypoxia. Studies investigating whether asparagine hydroxylation is a general regulatory oxygen-dependent modification hav...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080695 | MassIVE
TranscriptomicsTranscription profiling of human mesenchymal stromal cells to reveal senescence associated gene expression changes
Transcription profiling of human mesenchymal cells (MSCs) after ex vivo expansion under culture conditions supporting extensive cell proliferation. Highly efficient cell expansion within short time (~40 days) and comparison of gene expression profiles from MSCs after primary seeding, defined as earl...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-MEXP-1997 | biostudies-arrayexpress
ProteomicsM.tuberculosis - Whole organism, absolute concentration (Schubertetal,cellhostmicrobe2014)
abundance based on absolute concentration, Interaction consistency score: 1.0, Coverage: 46
ORGANISM(S): 83332 
2014-00-00 | 2118471723 | PAXDB
ProteomicsMtb_H37Rv_ETHZ
Mtb_H37Rv_OGE24
ORGANISM(S): Mycobacterium Tuberculosis 
2013-12-31 | PAe003619 | PeptideAtlas
ProteomicsMbov_BCG_ETHZ
M. bovis BCG (the vaccine strain for M. tuberculosis) from ETH Zurich.
ORGANISM(S): Mycobacterium Tuberculosis 
2013-12-31 | PAe001580 | PeptideAtlas
GenomicsWhole Genome Profiling to Detect Schizophrenia Methylation Markers

Schizophrenia (SCZ) is a devastating psychiatric disorder. The aim of this study was to detect DNA methylation (5meC) profiles in whole blood associated with SCZ. The sample consisted of schizophrenia cases and controls selected from national population registers in Sweden. We employed MBD protei...

phs000608.v1.p1 | EGA
GenomicsSweden-Schizophrenia Population-Based Case-Control Exome Sequencing

Current findings of the genetic risk of schizophrenia and bipolar disorder emerging from genome wide association studies (GWAS) support a highly polygenic model displaying the full spectrum of causal alleles that includes the extremes of rare, penetrant alleles as well as common alleles of small ...

phs000473.v1.p1 | EGA
TranscriptomicsIdentification of miR-4423 as a Primate-Specific microRNA Highly Expressed in Ciliated Airway Epithelium and Associated with Lung Cancer [high throughput sequencing]
Smoking is a significant risk factor for lung cancer, the leading cause of cancer-related deaths worldwide. While microRNAs are regulators of many airway gene-expression changes induced by smoking, their role in modulating changes associated with lung cancer in these cells remains unknown. Here, we ...
ORGANISM(S): Homo sapiens 
2013-10-08 | E-GEOD-32726 | biostudies-arrayexpress
UnknownIdentification of miR-4423 as a Primate-Specific microRNA Highly Expressed in Ciliated Airway Epithelium and Associated with Lung Cancer [high throughput sequencing]
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-32726 | biostudies-other
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