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ProteomicsGenotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1
Pattern-triggered immunity (PTI) is a central component of plant immunity. Activation of PTI relies on the recognition of microbe-derived structures, termed patterns, through plant encoded surface-resident pattern recognition receptors (PRRs). We have identified proteobacterial translation initiatio...
ORGANISM(S): Escherichia coli 
2022-03-03 | PXD031124 | Pride
Pattern recognition receptor Proteobacterial protein translation initiation factor 1 Plant immunity 
ProteomicsElongator is required for pattern recognition receptor and type I interferon signaling in macrophages.
Innate immune detection of pathogens by macrophages requires a rapid and large scale mobilisation of cellular resources towards an appropriate immune response, mainly involving altered protein expression. Pathogen recognition is mediated by pattern recognition receptor (PRR) sensing of conserved mic...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-22 | PXD064630 | Pride
Innate immunity  interferon  interferon regulatory factor (irf)  lipopolysaccharide (lps)  macrophage  pattern recognition receptor (prr)  stat transcription factor  toll-like receptor 4 (tlr4)  virus  elongator 
GenomicsBacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
Bacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
PRJNA835140 | ENA
TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alt...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-36933 | biostudies-arrayexpress
GenomicsRNA-seq analysis of transcriptome reprofiling triggered by different pattern-recognition receptor types
RNA-seq analysis of transcriptome reprofiling triggered by different pattern-recognition receptor types
PRJNA549850 | ENA
TranscriptomicsEffect of Drosophila immune proteins on gene expression in E. coli
Interaction between the host and invading pathogen determines the fate of both organisms during the infectious state. The host is equipped with a battery of immune reactions, while the pathogen displays a variety of mechanisms to compromise host immunity. Although bacteria alter their pattern of g...
ORGANISM(S): Escherichia coli 
2015-01-13 | E-GEOD-61604 | biostudies-arrayexpress
Genomics
Pattern recognition receptor identification of Vibrio parahaemolyticus in oysters
PRJNA748527 | ENA
TranscriptomicsBacterial pattern recognition in C. elegans by the nuclear hormone receptor NHR-86/HNF4
Pattern recognition of bacterial products by host receptors is essential for pathogen sensing in many metazoans. Caenorhabditis elegans, however, do not utilize canonical pattern recognition receptors to activate innate immunity toward bacterial pathogens. Whether other mechanisms evolved in nematod...
ORGANISM(S): Caenorhabditis elegans 
2023-02-07 | GSE202258 | GEO
TranscriptomicsGene expression study reveals compromised Pattern Recognition Receptors and Interferon Signaling in fullterm Low birth Weight newborns
Low Birth Weight (LBW) newborns (with weight less than 2500g) suffer a higher frequency and severity of microbial infection than normal birth weight (NBW) newborns. Morbidity and mortality of LBW infants due to infectious diseases are known to be high and it has been associated with compromised immu...
ORGANISM(S): Homo sapiens 
2012-01-15 | E-GEOD-29807 | biostudies-arrayexpress
ProteomicsGreen leaf volatiles co-opt proteins involved in molecular pattern signaling in plant cells
The green leaf volatiles (GLVs) Z-3-hexen-1-ol (Z3-HOL) and Z-3-hexenyl acetate (Z3-HAC) are airborne infochemicals released from damaged plant tissues that induce defenses and developmental responses in receiver plants, but little is known about their mechanism of action. We found that Z3-HOL and Z...
ORGANISM(S): Solanum peruvianum 
2024-02-19 | PXD047832 | Pride
Map kinase (mapk) Damp Systemin Green leaf volatiles (glvs) Molecular pattern Volatile organic compounds (vocs) Phosphoproteomics Pattern recognition receptor 
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