Effect of Drosophila immune proteins on gene expression in E. coli

ABSTRACT: Interaction between the host and invading pathogen determines the fate of both organisms during the infectious state. The host is equipped with a battery of immune reactions, while the pathogen displays a variety of mechanisms to compromise host immunity. Although bacteria alter their pattern of gene expression when they enter host organisms, studies to elucidate the mechanism behind this are only in their infancy. In the present study, we examined the possibility that host immune proteins directly participate in the change of gene expression in bacteria. To this end, Escherichia coli was treated with a mixture of the extracellular region of membrane-bound peptidoglycan recognition protein LC (PGRP-LC) and the antimicrobial peptide attacin of Drosophila, and subsequently subjected to D

ORGANISM(S): Escherichia coli

SUBMITTER: Yuji Nakai 

PROVIDER: E-GEOD-61604 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress