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ProteomicsReticular fibroblasts counteract radiotherapy-induced head and neck tumor regression through Tenascin-C
Head and neck squamous cell carcinoma (HNSCC) patients have a very short survival. To improve patient survival, there is an emerging need for a better understanding of the obstacles of ionizing irradiation (IR), besides surgery, currently the best treatment option for HNSCC. A confounding factor is ...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-14 | PXD060164 | Pride
Tenascin-c Radiotherapy Reticular fibroblasts Tumor 
MetabolomicsLipid mediators of inflammation in BALF 3-11 days after infection with influenza
Bioactive lipid mediators play a crucial role in the induction and resolution of inflammation. To elucidate their involvement during influenza infection, liquid chromatography/mass spectrometry lipidomic profiling of 141 lipid species was performed on a mouse influenza model using two viruses of sig...
2013-05-30 | MTBLS33 | MetaboLights
TranscriptomicsTranscription profiling of mouse liver from JNK knocked down animals
Liver-specific Knockdown of JNK1 Up-regulates Proliferator-activated Receptor Coactivator 1 and Increases Plasma Triglyceride despite Reduced Glucose and Insulin Levels in Diet-induced Obese Mice. The c-Jun N-terminal kinases (JNKs) have been implicated in the development of insulin resistance, dia...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7648 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat cortex regions
The neocortex of the mammalian brain is comprised by six distinct layers with neuronal subtypes that appear indistinguishable from one cortical area to the next. Correspondingly, global gene expression seems to be almost identical across the cerebral cortex and only a few genes have so far been repo...
ORGANISM(S): Rattus norvegicus 
2010-12-31 | E-TABM-1019 | biostudies-arrayexpress
ProteomicsMulti-OMICS data of a Hyper IgD Syndrome family
The aim of this study was to understand why two siblings carrying both the same homozygous causal mutation for the auto-inflammatory disease hyper IgD show opposite phenotypes, i.e. the first being asymptomatic, the second presenting all classical characteristics of the disease. As compared to studi...
ORGANISM(S): Homo sapiens (Human) 
2019-10-24 | PXD009063 | Pride
Proteogenomics analysis - differential analysis - hyper igd syndrome - single amino acid variant characterization 
ProteomicsRedox proteomic analysis of H2O2 -treated Jurkat cells and effects of bicarbonate and peroxiredoxins 1 and 2
Oxidation of thiol proteins and redox signaling occur in cells exposed to H2O2 but mechanisms are unclear. We used redox proteomics to seek evidence of oxidation of specific proteins either by a mechanism involving reaction of H2O2 with CO2/bicarbonate to give the more reactive peroxymonocarbonate...
ORGANISM(S): Homo Sapiens 
2024-07-08 | PXD053738 |
TranscriptomicsComparative genomic hybridization by array of glioblastoma-derived neural stem cells
Comparative genomic hybridization of glioma neural stem cells and normal human reference DNA
ORGANISM(S): Homo sapiens 
2012-09-21 | E-MTAB-972 | biostudies-arrayexpress
TranscriptomicsDigital expression analysis of glioma neural stem cells
High-throughput sequencing of transcript tags from normal and glioblastoma-derived neural stem cell lines
ORGANISM(S): Homo sapiens 
2012-09-21 | E-MTAB-971 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mosquitos fed blood infected with two alternative P. berghei strains: wild type (wt) or an invasion-deficient, CTRP (Circumsporozoite- and TRAP-related protein) knockout (ko) strain
Female mosquitoes fed with blood infected with two alternative P. berghei strains: wild type (wt) or an invasion-deficient, CTRP (Circumsporozoite- and TRAP-related protein) knockout (ko) strain. We used CTRPko-infected midguts as reference, as they experience pre-invasion conditions similar to thos...
ORGANISM(S): Anopheles gambiae 
2005-07-12 | E-MEXP-378 | biostudies-arrayexpress
no omics definedTranscription profiling of teicoplanin-susceptible strain of S.aureus and its teicoplanin-resistant derivative
Changes in transcriptome of S. aureus linked with acquisition of teicoplanin resistance and reduced autolysis. Comparison of RNA profiling of the teicoplanin-susceptible parental strain (MRGR3)with its teicoplanin-resistant derivative (14-4).
ORGANISM(S): Staphylococcus aureus 
2007-01-01 | E-MEXP-738 | biostudies-arrayexpress
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