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Antibiotics revolutionized medicine, however, it is now clear that broad-spectrum antibiotics alter the composition and function of the host’s microbiome. The microbiome plays a key role in human health and its perturbation is increasingly recognized as contributing to many human diseases. Wide spre...
2021-01-11 | MTBLS1257 | MetaboLights
Aims: Loss of nuclear TDP-43 characterises sporadic and most familial forms of amyotrophic lateral sclerosis (ALS). TDP-43 (encoded by TARDBP) has multiple roles in RNA processing. We aimed to determine whether 1) RNA splicing dysregulation is present in lower motor neurons in ALS and in a motor neu...
ORGANISM(S): Mus musculus 
A custom Illumina genotyping array, the OncoArray. The array includes a genome-wide backbone, comprising 230,000 SNPs tagging most common genetic variants, together with dense mapping of known susceptibility regions, rare variants from sequencing experiments, pharmacogenetic markers, and cancer-rela...
Germline genotype data on 56,479 ovarian cancer cases and controls
Data Access Committee EGAC00001000616
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
WTCCC1 project Breast cancer (BC) samples
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