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TranscriptomicsCathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis
Cavitation in tuberculosis (TB) enables highly efficient person-to-person aerosol transmission. Currently, a number of hypotheses exist regarding the mechanisms underlying this process. To explore this process, we undertook an unbiased next-generation transcriptional analysis of samples from cavity ...
ORGANISM(S): Oryctolagus cuniculus 
2015-11-03 | E-GEOD-68206 | biostudies-arrayexpress
Methylation profiling[E-TABM-482] DNA methylome of human spermatozoa
Genome-wide DNA methylation profile of human spermatozoa using the meDIP technique and massively parallel sequencing. DNA methylation is an indispensible epigenetic modification required for regulating the expression of mammalian genomes. Immunoprecipitation-based methods for DNA methylome analysis ...
ORGANISM(S): Homo sapiens 
2011-02-05 | GSE25686 | GEO
UnknownAge-dependent changes in health status in the Childhood Cancer Survivor cohort.
Not available
S-EPMC4314595 | biostudies-literature
UnknownEmergence of multidrug-resistant Salmonella Paratyphi B dT+, Canada.
Not available
S-EPMC3323318 | biostudies-literature
UnknownImpact of Prognostic Discussions on the Patient-Physician Relationship: Prospective Cohort Study.
Not available
S-EPMC5773842 | biostudies-literature
MetabolomicsHost-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However, further medicinal development is largely restric...
2018-02-12 | MTBLS452 | MetaboLights
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownCollagen VI deficiency reduces muscle pathology, but does not improve muscle function, in the γ-sarcoglycan-null mouse.
Not available
S-EPMC4787905 | biostudies-literature
GenomicsHomo sapiens
[E-TABM-482] DNA methylome of human spermatozoa
PRJNA135835 | ENA
TranscriptomicsTranscription profiling of murine livers after resveratrol treatment of mice on a high-calorie diet
Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including yeast, worms, and flies. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction (CR). Here we show that resveratr...
ORGANISM(S): Mus musculus 
2008-06-21 | E-GEOD-6089 | biostudies-arrayexpress
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