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TranscriptomicsSaccharomyces cerevisiae deletion collections chemogenomic screen with sr7575
Growth assay in the presence of a toxic chemical (sr7575) that uses the barcoded collections of yeast gene deletions (haploid, diploid, DamP) to identify deletion strains that are hypersensitive to the drug. Two-condition experiment – growth of a pool of strains in the presence or absence of the d...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-09 | E-GEOD-60934 | biostudies-arrayexpress
UnknownBCL11A frameshift mutation associated with dyspraxia and hypotonia affecting the fine, gross, oral, and speech motor systems.
Not available
S-EPMC5765401 | biostudies-literature
UnknownPhase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer.
Not available
S-EPMC5321045 | biostudies-literature
GenomicsSaccharomyces cerevisiae
Saccharomyces cerevisiae deletion collections chemogenomic screen with sr7575
PRJNA259859 | ENA
TranscriptomicsTranscription profiling of CACNA1E overexpression in human embryonic kidney HEK293 cells to investigate the involvement of CACNA1E in Wilms tumorigenesis
Wilms tumour (nephroblastoma) is the most common paediatric renal tumour, affecting 1 in 10,000 children. Despite the excellent survival of patients treated with a combination of surgery, chemotherapy and radiotherapy, approximately 15% will relapse and die of this disease. We have identified CACNA1...
ORGANISM(S): Homo sapiens 
2006-12-01 | E-MEXP-587 | biostudies-arrayexpress
UnknownZika virus-based immunotherapy enhances long-term survival of rodents with brain tumors through upregulation of memory T-cells.
Not available
S-EPMC7529292 | biostudies-literature
UnknownPhase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group.
Not available
S-EPMC3158598 | biostudies-literature
GenomicsTargets of Ty3 transposition in Saccharomyces cerevisiae
The goal of these experiments was to define the targets of Ty3 transposition in Saccharomyces cerevisiae. Ty3 is a retroviruslike element that is found at the transcription initiation site of chromosomal tRNA genes. A Ty3 that can be induced by growth in galactose-containing medium and which was ma...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-02 | E-GEOD-31820 | biostudies-arrayexpress
TranscriptomicsPrediction of in vivo radiation dose in radiotherapy patients using ex vivo and in vivo gene expression signatures
After defining a gene expression signature that predicted radiation exposure dose with high accuracy in human peripheral white blood cells irradiated ex vivo, we now demonstrate the predictive power of gene expression signatures in blood from patients undergoing total body irradiation. Using whole ...
ORGANISM(S): Homo sapiens 
2011-01-31 | E-GEOD-20162 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 17 favourable histology Wilms tumour samples taken at immediate nephrectomy in order to identify changes in DNA copy number associated with clinical outcome
We have carried out microarray-based comparative genomic hybridisation (arrayCGH) on 17 Favourable histology Wilms tumour samples taken at immediate nephrectomy in order to identify changes in DNA copy number associated with clinical outcome. Tumour DNA was co-hybridised with normal female genomic D...
ORGANISM(S): Homo sapiens 
2006-05-11 | E-TABM-13 | biostudies-arrayexpress
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