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UnknownMyotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons.
Not available
S-EPMC9233098 | biostudies-literature
MetabolomicsGlycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Central carbon metabolism is highly conserved across microbial species, but can catalyze very different pathways depending on the organism and their ecological niche. Here, we study the dynamic reorganization of central metabolism after switches between the two major opposing pathway configurations ...
2022-01-11 | MTBLS3887 | MetaboLights
MetabolomicsMass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

Human brain organoids are emerging models to study human brain development and pathology as they recapitulate the development and characteristics of major neural cell types, and enable manipulation through an in vitro system. Over the past decade, with the advent of spatial technologies,...

2023-05-23 | MTBLS7565 | MetaboLights
UnknownProper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.
Not available
S-EPMC9990683 | biostudies-literature
UnknownAutism genes converge on asynchronous development of shared neuron classes.
Not available
S-EPMC8852827 | biostudies-literature
UnknownComparative genomics of plant-associated Pseudomonas spp.: insights into diversity and inheritance of traits involved in multitrophic interactions.
Not available
S-EPMC3390384 | biostudies-literature
UnknownGenetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington's Disease.
Not available
S-EPMC7156911 | biostudies-literature
UnknownCAG Repeat Not Polyglutamine Length Determines Timing of Huntington's Disease Onset.
Not available
S-EPMC6700281 | biostudies-literature
UnknownContext-dependent neocentromere activity in synthetic yeast chromosome VIII.
Not available
S-EPMC10667555 | biostudies-literature
UnknownMultivariate clustering of progression profiles reveals different depression patterns in prodromal Huntington disease.
Not available
S-EPMC4640959 | biostudies-literature
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