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ProteomicsG9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered TCR-T cells against hepatocellular carcinoma
Engineered T cells transiently expressing tumor-targeting receptors are an attractive form of engineered T cell therapy as they carry no risk of insertional mutagenesis or long-term adverse side-effects. However, multiple rounds of treatment are often required, increasing patient discomfort and cost...
ORGANISM(S): Homo Sapiens (human) 
2023-01-19 | PXD039542 | JPOST Repository
TranscriptomicsBulk RNA-seq of the human fetal neocortex, lateral ganglionic eminence and medial ganglionic eminence at 7, 9, 11 and 20 post-conceptional weeks
Deep transcriptional profiling of the human neocortex, lateral ganglionic eminence (LGE) and medial ganglionic eminences (MGE), from 7 to 20 post-conceptional weeks (pcw), for de novo lincRNAs discovery and to establish a unique coding and non-coding gene signature for the three different regions.
ORGANISM(S): Homo sapiens 
2021-05-13 | E-MTAB-8893 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of the human fetal lateral ganglionic eminence at 7, 9 and 11 post-conceptional weeks
Single-cell RNA-seq of the LGE between 7 and 11 pcw was used to uncover the different cell populations of the developing human striatum and how cells transition from early progenitors to mature medium spiny neuron (MSNs) together with the discovery of their unique coding and non-coding transcription...
ORGANISM(S): Homo sapiens 
2021-05-13 | E-MTAB-8894 | biostudies-arrayexpress
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