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Polycomb repressive complexes 1 and 2 (PRC1 and 2) repress lineage inappropriate genes during development to maintain proper cellular identities. To reveal the function of a variant PRC1 containing PCGF1 (PCGF1-PRC1), we prepared PCGF1 interacting proteins by immunoprecipitation and characterized th...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD036330 | Pride
The transcription factor Runx1 is essential for the establishment of definitive hematopoiesis during embryonic development. In adult blood homeostasis, Runx1 plays a pivotal role in the maturation of lymphocytes and megakaryocytes. Furthermore, Runx1 is required for the regulation of hematopoietic s...
ORGANISM(S): Mus musculus 
Polycomb repressive complexes 1 and 2 (PRC1 and 2) repress lineage inappropriate genes during development to maintain proper cellular identities. To reveal the function of a variant PRC1 containing PCGF1 (PCGF1-PRC1), we prepared PCGF1 interacting proteins by immunoprecipitation and characterized th...
ORGANISM(S): Mus Musculus (mouse) 
Transcriptommic profiling of hematopoietic progenitor cells following PCGF1 loss
Gene regulation by PCGF1 in hematopoietic progenitor cells
Gene regulation by PCGF1 in hematopoietic progenitor cells [ChIP, MNaseSeq]
Transcriptommic profiling of hematopoietic progenitor cells following PCGF1 loss [RNA-Seq]
Gene regulation by PCGF1 in hematopoietic progenitor cells [ChIP and MNaseSeq]
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