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TranscriptomicsGene expression of rat cerebellum in a new animal model of hepatic encephalopathy (HE)
Identify differentially expressed genes related to the neurodegenerative process in a new animal model of hepatic encephalopathy (HE). The animal model consists on the simulation of several bouts of HE in PCA rats, being the precipitant factors of the episodes ammonia (NH3) and/or lipopolisaccharide...
ORGANISM(S): Rattus norvegicus 
2015-07-29 | E-GEOD-71425 | biostudies-arrayexpress
UnknownPD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy.
Not available
S-EPMC10086742 | biostudies-literature
ProteomicsProteome of the cortex of old Pink1-SNCA A53T double mutant Parkinson mice
Parkinson's Disease (PD) is primarily caused by aggregates of alpha synuclein (SNCA) in dopaminergic neurons of the substantia nigra, but PD is a systemic disease and may lead to PD-associated dementia complex. PD-associated encephalopathy is a late manifestation in PD patients at risk for example o...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-21 | PXD039172 | Pride
Lc-ms/ms Mutant alpha synuclein (snca-a53t) Parkinson's disease Pten-induced kinase 1 Pd-associated encephalopathy 
TranscriptomicsPrion infected ScN2a and GT1
A comparison of prion infected and non-infected samples from neuroblastoma cells (N2a), and a comparison of prion infected and non-infected samples from hypothalmus cells (GT1). 11 dual-color DNA-chip hybridizations of cDNAs were made. Keywords: other
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-1803 | biostudies-arrayexpress
TranscriptomicsDevelopmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus
A key event in the pathogenic process of prion diseases is the conversion of the cellular prion protein (PrPC) to an abnormal and protease-resistant isoform (PrPSc). Mice lacking PrP are resistant to prion infection, and down-regulation of PrPC during prion infection prevents neuronal loss and the p...
ORGANISM(S): Mus musculus 
2011-04-12 | E-GEOD-21718 | biostudies-arrayexpress
UnknownAssociation between dietary β-carotene intake with Parkinson's disease and all-cause mortality among American adults aged 40 and older (NHANES 2001-2018).
Not available
S-EPMC11472250 | biostudies-literature
TranscriptomicsLoss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated Pdl1 Expression: Epithelial Cells
Lung squamous cell carcinoma (SCC) is a deadly disease for which current treatments are inadequate. We demonstrate that bi-allelic inactivation of Lkb1 and Pten in the mouse lung led to SCC that recapitulated the histology, gene expression and microenvironment found in human disease. Lkb1/Pten-null ...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-54351 | biostudies-arrayexpress
UnknownThe effects of different types of Tai Chi exercises on motor function in patients with Parkinson's disease: A network meta-analysis.
Not available
S-EPMC9465240 | biostudies-literature
ProteomicsSuper-SILAC analysis of human lung primary tumor-derived xenografts LC-MS/MS
Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancers, and is subdived into 2 major histological subtypes: adenocacinoma (ADC) and squamous cell carcinoma (SCC). Super-SILAC methodology was used to facilitate the quantitative comparisons of human primary tumor-derived xenograft proteom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-02 | MSV000079881 | MassIVE
UnknownGinsenoside Rg1 ameliorates stress-exacerbated Parkinson's disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle.
Not available
S-EPMC11747340 | biostudies-literature
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