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MetabolomicsMicrobial community-scale metabolic modelling predicts personalized short-chain fatty acid production profiles in the human gut
Microbially derived short-chain fatty acids (SCFAs) in the human gut are tightly coupled to host metabolism, immune regulation and integrity of the intestinal epithelium. However, the production of SCFAs can vary widely between individuals consuming the same diet, with lower levels often associated ...
2026-05-26 | MTBLS2308 | MetaboLights
MetabolomicsGenome-scale metabolic modelling of responses to polymyxins in Pseudomonas aeruginosa
Background: Pseudomonas aeruginosa often causes multidrug-resistant infections in immunocompromised patients and polymyxins are often used as the last-line therapy. Alarmingly, resistance to polymyxins has been increasingly reported worldwide recently. To rescue this last-resort class of antibiotics...
2018-02-28 | MTBLS630 | MetaboLights
ProteomicsApplying log-normal peak fitting to parallel reaction monitoring data analysis.
To support quantitative data analysis, we have developed a software, peakfit, that fits acquired chromatographic data to the log-normal peak equation and reports the calculated peak parameters. To demonstrate the capabilities of this approach, we provide hereby four example datasets: (1) 15 QCs of a...
ORGANISM(S): Homo sapiens (Human) 
2021-07-26 | PXD026875 | Pride
Data processing Peak modelling Peak fitting Parallel reaction monitoring Software tool 
UnknownOccuPeak: ChIP-Seq peak calling based on internal background modelling.
Not available
S-EPMC4061025 | biostudies-literature
UnknownShould public health policy exempt cases with low viral load from isolation during an epidemic?: a modelling study.
Not available
S-EPMC12284519 | biostudies-literature
UnknownThe effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study.
Not available
S-EPMC7158905 | biostudies-literature
UnknownLockdown as a last resort option in case of COVID-19 epidemic rebound: a modelling study.
Not available
S-EPMC8176673 | biostudies-literature
ProteomicsInsights into the biodegradation of two persistent fluorinated fungicides by coupling metabolic modelling with metaproteogenomics
Epoxiconazole (EPO) and fludioxonil (FLU) are fluorinated fungicides characterized by their extremely high environmental persistence and ecotoxicity. Given their decades-old use in the agrochemical sector, EPO and FLU have become frequent pollutants of terrestrial and aquatic ecosystems. And yet, no...
ORGANISM(S): metagenomes 
2026-01-23 | PXD067833 | Pride
Epoxiconazole  fludioxonil  metagenomics  metaproteomics  defluorination  
UnknownModelling height in adolescence: a comparison of methods for estimating the age at peak height velocity.
Not available
S-EPMC5743008 | biostudies-literature
GenomicsMathematical modelling reveals a ribosome level-induced survival checkpoint in drug-tolerant cancer persister cells
Mathematical modelling reveals a ribosome level-induced survival checkpoint in drug-tolerant cancer persister cells
PRJNA1387408 | ENA
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