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MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
MetabolomicsTime-resolved decoding of metabolic signatures of in vitro growth of the hemibiotrophic pathogen Colletotrichum sublineolum
Metabolomics has emerged as a powerful approach to comprehensively interrogate cellular biochemistry. As such, we applied an untargeted liquid chromatography-mass spectrometry metabolomic strategy to elucidate metabolome changes in the anthracnose-causing hemibiotrophic sorghum pathogen, Colletotric...
2022-05-30 | MTBLS735 | MetaboLights
UnknownComparison of [11C]-PBR28 Binding Between Persons Living With HIV and HIV-Uninfected Individuals.
Not available
S-EPMC8053041 | biostudies-literature
UnknownOlive oil consumption, plasma metabolites, and risk of type 2 diabetes and cardiovascular disease.
Not available
S-EPMC10720204 | biostudies-literature
MetabolomicsMetabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs)
Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprogramming induces drastic changes in the transcripti...
2021-08-20 | MTBLS608 | MetaboLights
UnknownGenomic features of rapid versus late relapse in triple negative breast cancer.
Not available
S-EPMC8130400 | biostudies-literature
UnknownDevelopment and clinical application of a deep learning model to identify acute infarct on magnetic resonance imaging.
Not available
S-EPMC8828773 | biostudies-literature
UnknownRecombination Suppression Drives Expansion of the Drosophila Dot Chromosome.
Not available
S-EPMC12728734 | biostudies-literature
MetabolomicsLinking gastrointestinal microbiota and metabolome dynamics to clinical outcomes in pediatric hematopoietic stem cell transplantation

BACKGROUND: Hematopoietic stem cell transplantation is a curative procedure for a variety of conditions. Despite major advances, a plethora of adverse clinical outcomes can develop post-transplantation including graft-versus-host disease and infections, which remain the major cau...

2022-05-11 | MTBLS4065 | MetaboLights
UnknownIdentification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
Not available
S-EPMC8422160 | biostudies-literature
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