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TranscriptomicsTET2 loss-of-function mutations associate with a DNA hypermethylation signature in diffuse large B-cell lymphoma (DNA methylation)
Genome wide DNA methylation profiling of patient samples with TET2 mutations and Wild type TET2 status . The Illumina Infinium HumanMethylation 450_15017482_v.1.1 was used to obtain DNA methylation profiles across approximately 482,421 CpGs in fresh frozen lymphoma samples. Samples include 19 TET2...
ORGANISM(S): Homo sapiens 
2013-10-10 | E-GEOD-37362 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of TET2 wild type and TET2 mutant patients with diffuse large B-cell derived lymphoma
Global gene expression in TET2 mutant and Wild type patients. We performed an integrated analysis of global DNA methylation and gene expression data to investigate the effects of DNA hypermethylation on gene expression. Total RNA was isolated from 4 TET2mut and 5 TET2wt were isolated using standard...
ORGANISM(S): Homo sapiens 
2013-10-10 | E-GEOD-37363 | biostudies-arrayexpress
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