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TranscriptomicsCCAAT/enhancer-binding protein alpha target genes in myeloid progenitor cells uncovered by chromatin IP
CCAAT/enhancer-binding protein alpha (C/EBPM-NM-1) is a lineage-specific transcription factor that directs development of granulocytes. To obtain insights into the genome-wide transcriptome of wild type C/EBPM-NM-1, we have performed chromatin immunoprecipitation on DNA promoter microarrays (ChIP-ch...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-19321 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially regulated splice variants and novel exons in glial brain tumors using exon arrays
Aberrant splice variants are involved in the initiation and/or progression of glial brain tumors. We therefore set out to identify splice variants that are differentially expressed between histological subgroups of gliomas. Splice variants were identified using a novel platform that profiles the exp...
ORGANISM(S): Homo sapiens 
2008-01-28 | E-GEOD-9385 | biostudies-arrayexpress
GenomicsThe Growth factor independence 1 (GFI1) 36N variant predisposes to Acute Myeloid Leukemia (AML) by inducing epigenetic changes at the Hoxa9 locus
GFI136N is a coding Single Nucleotide Polymorphism (SNP) in the gene GFI1 that increases the risk for Acute myeloid leukemia (AML) by 60%. It is present in 3-5% of Caucasians and has a prevalence of 12% among AML patients. We generated knockin mice expressing either the human GFI136N variant or the ...
ORGANISM(S): Mus musculus 
2012-12-04 | E-GEOD-31657 | biostudies-arrayexpress
UnknownInherited CARD9 deficiency in otherwise healthy children and adults with Candida species-induced meningoencephalitis, colitis, or both.
Not available
S-EPMC4831587 | biostudies-literature
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