Sort   by:  
 Page size 
ProteomicsDT2216 is a specific BCL-XL PROTAC
To validate the specificity of DT2216, we used the stable isotope labeling with amino acids in cell culture (SILAC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomics to analyze the changes in proteins in WI-38 normal human diploid fibroblasts after DT2216 and DT2216NC tr...
ORGANISM(S): Homo sapiens (Human) 
2019-10-08 | PXD010878 | Pride
Dt2216 bcl-xl protac silac lc-ms/ms 
UnknownDiscovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines.
Not available
S-EPMC7325632 | biostudies-literature
UnknownA selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Not available
S-EPMC6898785 | biostudies-literature
UnknownBim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
Not available
S-EPMC2786688 | biostudies-literature
UnknownSmall Gold(I) and Gold(I)-Silver(I) Clusters by C-Si Auration.
Not available
S-EPMC7317441 | biostudies-literature
TranscriptomicsGENCODE Batch VIII c: determining lncRNA transcript 5' and 3'-ends by RACE-PCR / 454 sequencing
As part of the ENCODE consortium the GENCODE project is producing a reference gene set through manual and automated gene prediction. In the current phase of ENCODE we have found strong evidence that many lncRNAs transcript termini are still unknown. This experiment aims to set up an experimental val...
ORGANISM(S): Homo sapiens 
2013-05-17 | E-MTAB-1665 | biostudies-arrayexpress
UnknownChk1 Inhibition Potently Blocks STAT3 Tyrosine705 Phosphorylation, DNA-Binding Activity, and Activation of Downstream Targets in Human Multiple Myeloma Cells.
Not available
S-EPMC8898301 | biostudies-literature
TranscriptomicsGENCODE Batch VIII a: determining lncRNA transcript 5' and 3'-ends by RACE-PCR / 454 sequencing
As part of the ENCODE consortium the GENCODE project is producing a reference gene set through manual and automated gene prediction. In the current phase of ENCODE we have found strong evidence that many lncRNAs transcript termini are still unknown. This experiment aims to set up an experimental val...
ORGANISM(S): Homo sapiens 
2012-08-31 | E-MTAB-1222 | biostudies-arrayexpress
UnknownThe effect of fluid shear stress on fibroblasts and stem cells on plane and groove topographies.
Not available
S-EPMC6973306 | biostudies-literature
UnknownHierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset.
Not available
S-EPMC9668310 | biostudies-literature
Sort   by:  
 Page size