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TranscriptomicsTargeting c-MYC by antagonizing PP2A inhibitors in breast cancer
Inhibition of SET by siRNA or SET antagonist and CIP2A by siRNA can downregulate c-MYC and c-MYC target genes. Cells were treated with a SET antagonist (1μMOP449) for 12 hours, or siRNA for 48 hours.
ORGANISM(S): Homo sapiens 
2014-05-28 | E-GEOD-58008 | biostudies-arrayexpress
TranscriptomicsProfiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing
Status epilepticus (SE) is a life-threatening condition that can give rise to a number of neurological disorders, including learning deficits, depression, and epilepsy. Many of the effects of SE appear to be mediated by alterations in gene expression. To gain deeper insight into how SE affects the t...
ORGANISM(S): Mus musculus 
2015-08-27 | E-GEOD-72402 | biostudies-arrayexpress
TranscriptomicsRNAseq of primary human gallbladder cells, reprogrammed human gallbladder cells, and human pancreatic beta cells
We determined the global gene expression profiles of primary human gallbladder cells and genetically reprogrammed human gallbladder cells and compared with pancreatic beta cells to ascertain the degree of cellular transdifferentatiation of insulin-producing human gallbladder cells to become beta-lik...
ORGANISM(S): Homo sapiens 
2017-08-02 | E-MTAB-5556 | biostudies-arrayexpress
TranscriptomicsTargeted deletion of miR-132/212 impairs memory and alters the hippocampal transcriptome
miR-132 and miR-212 are structurally-related microRNAs that have been found to exert powerful modulatory effects within the central nervous system (CNS). Notably, these microRNAs are tandomly processed from the same non-coding transcript, and share a common seed sequence: thus it has been difficult ...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-73413 | biostudies-arrayexpress
UnknownDecline in the number of patients with meningitis in German hospitals during the COVID-19 pandemic.
Not available
S-EPMC8938731 | biostudies-literature
UnknownHeterogeneity of treatment preferences in the absence of guideline recommendations - a case vignette study in colorectal cancer tumor boards in Germany, Austria and Switzerland.
Not available
S-EPMC12505869 | biostudies-literature
UnknownBaseline characteristics of patients with acute ischaemic stroke included in the randomised controlled Find-AF 2 trial.
Not available
S-EPMC12203715 | biostudies-literature
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