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Metabolic reprogramming is a hallmark of cancer. Herein we discover that the key glycolytic enzyme pyruvate kinase M2 isoform (PKM2), but not the related isoform PKM1, is methylated by co-activator-associated arginine methyltransferase 1 (CARM1). PKM2 methylation reversibly shifts the balance of met...
2021-07-30 | MTBLS533 | MetaboLights
In the THP-1 cell line, knockdown of PSMB10 expression was performed using lentivirus, with a control group set up.
ORGANISM(S): Homo Sapiens 
2024-12-10 | PXD058714 |
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