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TranscriptomicsOrganogenesis relies on the SoxC transcription factors for the survival of neural and mesenchymal progenitors
During organogenesis, neural and mesenchymal progenitor cells give rise to many cell lineages, but their molecular requirements for self-renewal and lineage decisions are incompletely understood. Here we show that their survival critically relies on the redundantly acting SoxC transcription factors ...
ORGANISM(S): Mus musculus 
2010-04-28 | E-GEOD-20740 | biostudies-arrayexpress
TranscriptomicsSpontaneous cell competition in U2OS human osteosarcoma cells.
The study compares the transcriptional profiles of U2OS human osteosarcoma cells and those of two single-cell derived sub-lines carrying a stably integrated H2BmCherry (U2OS-R1) or H2B-YFP (U2OS-YFP) expression cassette. U2OS-R1 and U2OS-YFP cell spontaneously undergo apoptosis upon co-culture with...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-MTAB-3204 | biostudies-arrayexpress
TranscriptomicsHippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas
The Hippo signaling pathway has become recognized as a context-dependent regulator of cell proliferation, differentiation, and apoptosis in species ranging from Drosophila to human. In this study, we sought to understand whether Hippo signaling plays a role in pancreatic development and organ homeos...
ORGANISM(S): Mus musculus 
2013-02-14 | E-GEOD-44298 | biostudies-arrayexpress
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