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TranscriptomicsM. tuberculosis transcriptional profile of delta pepD strain vs wild-type strain
pepD is regulated by a 2CS, MprAB, and impacts upon the regulation of sigE, an important M.tb sigma factor. Here we examine the global impact of gene regulation in a delta pepD mutant strain. Analysis compares total RNA from early log growth cultures of both wild-type and a delta pepD strain.
ORGANISM(S): Mycobacterium tuberculosis 
2009-10-29 | E-GEOD-17587 | biostudies-arrayexpress
GenomicsRNA-seq data of PEPD over-expressed vs NC GBM cells
RNA-seq data of PEPD over-expressed vs NC GBM cells
PRJNA1395369 | ENA
TranscriptomicsRNA-seq data of PEPD over-expressed vs NC GBM cells
Peptidase D (PEPD) is a cytosolic metallopeptidase previously reported to interact with nuclear p53, suppressing its phosphorylation and transcriptional activity to facilitate tumor progression in several cancer types, including bladder and colorectal cancer. However, the role of PEPD in glioma has ...
ORGANISM(S): Homo sapiens 
2026-03-15 | GSE315227 | GEO
TranscriptomicsM. tuberculosis transcriptional profile of delta pepD strain vs wild-type strain
pepD is regulated by a 2CS, MprAB, and impacts upon the regulation of sigE, an important M.tb sigma factor. Here we examine the global impact of gene regulation in a delta pepD mutant strain.
ORGANISM(S): Mycobacterium tuberculosis 
2009-10-30 | GSE17587 | GEO
UnknownPEPD is a pivotal regulator of p53 tumor suppressor.
Not available
S-EPMC5727116 | biostudies-literature
TranscriptomicsFlavivirus antagonism of type I interferon signaling reveals prolidase as a regulator of IFNAR1 trafficking and expression
Type I interferon (IFN-I) signals through two receptor subunits, IFNAR1 and IFNAR2, to regulate sterile and infectious immunity. IFNAR1 expression is tightly regulated to prevent autoimmunity although the mechanisms governing this are incompletely understood. We investigated the strategies used by t...
ORGANISM(S): Homo sapiens 
2015-07-08 | E-GEOD-64387 | biostudies-arrayexpress
UnknownFour novel PEPD alleles causing prolidase deficiency.
Not available
S-EPMC1918181 | biostudies-literature
UnknownPepD participates in the mycobacterial stress response mediated through MprAB and SigE.
Not available
S-EPMC2832534 | biostudies-literature
UnknownThe Pediatric Ependymoma Protein Database (PEPD).
Not available
S-EPMC5671472 | biostudies-literature
UnknownDysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance.
Not available
S-EPMC7617220 | biostudies-literature
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