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ProteomicsIL7R mutational activation can initiate Ph-like and PAX5 P80R precursor B-cell acute lymphoblastic leukemia
Interleukin-7 receptor α (encoded by IL7R) is essential for lymphoid development. Whether acute lymphoblastic leukemia (ALL)-related IL7R gain-of-function mutations can trigger leukemogenesis remains unclear. Here, we demonstrate that lymphoid-restricted mutant IL7R, expressed at physiological level...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD017147 | Pride
Acute lymphoblastic leukemia B cells 
UnknownA fusion peptide in preS1 and the human protein disulfide isomerase ERp57 are involved in hepatitis B virus membrane fusion process.
Not available
S-EPMC8282342 | biostudies-literature
UnknownInterleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia.
Not available
S-EPMC8671594 | biostudies-literature
UnknownAssessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study.
Not available
S-EPMC10469327 | biostudies-literature
UnknownFluid loading in abdominal surgery - saline versus hydroxyethyl starch (FLASH Trial): study protocol for a randomized controlled trial.
Not available
S-EPMC4687283 | biostudies-literature
UnknownInduction of haemodynamic travelling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging.
Not available
S-EPMC12159494 | biostudies-literature
Genomicsena-DATASET-CRUK-CI-16-05-2016-12:25:56:672-139 - samples
Targeted sequencing of 173 genes in 2433 primary breast tumours. Data includes 2433 tumour samples, 523 adjacent normal (breast) samples and 127 blood samples. Libraries were prepared with Illumina's Nextera custom enrichment kit targetting all the exons of the most frequently mutated breast cance...
EGAD00001002115 | EGA
UnknownImpact of alternative materials to plasticized PVC infusion tubings on drug sorption and plasticizer release.
Not available
S-EPMC6908714 | biostudies-literature
UnknownDM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus.
Not available
S-EPMC8775431 | biostudies-literature
UnknownPeanut oral immunotherapy in adolescents: study protocol for a randomized controlled trial.
Not available
S-EPMC4430989 | biostudies-literature
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