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UnknownExtracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression.

Objective

Intratumor heterogeneity drives cancer progression and therapy resistance. However, it has yet to be determined whether and how subpopulations of cancer cells interact and how this interaction affects the tumour.

Design

We have studied the spontaneous flow of extracellular v...
S-EPMC9271144 | biostudies-literature
UnknownAlterations in mucosa branched <i>N</i>-glycans lead to dysbiosis and downregulation of ILC3: a key driver of intestinal inflammation.
The perturbation of the symbiotic relationship between microbes and intestinal immune system contributes to gut inflammation and Inflammatory Bowel Disease (IBD) development. The host mucosa glycans (glycocalyx) creates a major biological interface between gut microorganisms and host immunity that r...
S-EPMC11810091 | biostudies-literature
UnknownPatient-physician discordance in assessment of adherence to inhaled controller medication: a cross-sectional analysis of two cohorts.
OBJECTIVE:We aimed to compare patient's and physician's ratings of inhaled medication adherence and to identify predictors of patient-physician discordance. DESIGN:Baseline data from two prospective multicentre observational studies. SETTING:29 allergy, pulmonology and paediatric secondary care outp...
S-EPMC6858182 | biostudies-literature
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