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TranscriptomicsTranscription profiling of mouse primary macrophages treated with the chemotherapeutic agent, 5,6-dimethylxanthenone-4-acetic acid,
Vascular disrupting agents (VDA) represent a novel approach to the treatment of cancer, resulting in collapse of tumor vasculature and tumor death. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) is a VDA currently in advanced Phase II clinical trials, yet its precise mechanism of action is unknown de...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7194 | biostudies-arrayexpress
UnknownLeucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.
Not available
S-EPMC12832182 | biostudies-literature
TranscriptomicsLKB1 modulates lung cancer differentiation and metastasis
Inherited mutation in LKB1 results in the Peutz-Jeghers syndrome (PJS), characterized by intestinal hamartomas and a modestly increased frequency of gastrointestinal and breast cancer1. Somatic inactivation of LKB1 occurs in human lung adenocarcinoma2-4, but its tumor suppressor role in this tissue ...
ORGANISM(S): Homo sapiens 
2007-08-28 | E-GEOD-6135 | biostudies-arrayexpress
UnknownKey Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.
Not available
S-EPMC7652061 | biostudies-literature
UnknownProtocol for an international multicenter, prospective, observational, non-competitive, study to validate and optimise prediction models of 90-day and 1-year allograft failure after liver transplantation: The global IMPROVEMENT Study.
Not available
S-EPMC12226705 | biostudies-literature
UnknownCharacterizing Emerging Canine H3 Influenza Viruses.
Not available
S-EPMC7182277 | biostudies-literature
UnknownAssociation of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye.
Not available
S-EPMC7903258 | biostudies-literature
UnknownRegional Nodal Irradiation in Early-Stage Breast Cancer.
Not available
S-EPMC4556358 | biostudies-literature
UnknownEffective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.
Not available
S-EPMC7326489 | biostudies-literature
UnknownGenetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.
Not available
S-EPMC6685441 | biostudies-literature
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