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UnknownGuanfacine Augmentation of a Combined Intervention of Computerized Cognitive Remediation Therapy and Social Skills Training for Schizotypal Personality Disorder.
Not available
S-EPMC6443471 | biostudies-literature
MetabolomicsJ-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis
1H nuclear magnetic resonance (NMR) spectroscopy-based metabolic phenotyping is now widely used for large-scale epidemiological applications. To minimize signal overlap present in 1D 1H NMR spectra, we have investigated the use of 2D J-resolved (JRES) 1H NMR spectroscopy for large-scale phenotyping ...
2018-07-23 | MTBLS540 | MetaboLights
TranscriptomicsRNA sequencing of endocrine resistant breast cancer
*** This submission includes RNA data, with DNA files available under a different accession number*** Purpose: Endocrine therapy resistance remains the greatest challenge for treating hormone receptor positive breast cancer patients. We aim to identify molecular mechanisms underlying endocrine ther...
ORGANISM(S): Homo sapiens 
2022-09-01 | E-MTAB-9917 | biostudies-arrayexpress
TranscriptomicsPOU2AF1 Functions in the Human Airway Epithelium to Regulate Expression of Host Defense Genes [RNA-Seq]
In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected expression of POU2AF1, a known transcription co-factor previously thought to be expressed only in lymphocytes. Lymphocyte contamination of human ai...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-60989 | biostudies-arrayexpress
TranscriptomicsPI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer
Activating mutations of PIK3CA are the most frequent genomic alterations in estrogen receptor (ER)-positive breast tumors and selective PI3Kα inhibitors are in clinical development. The activity of these agents, however, is not homogenous and only a fraction of patients bearing PIK3CA-mutant ER-posi...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-64033 | biostudies-arrayexpress
TranscriptomicsImpact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol
Objectives: The sequencing by the PolyA selection is the most common approach for library preparation. With limited amount or degraded RNA, alternative protocols such as the NuGEN have been developed. However, it is not yet clear how the different library preparations affect the downstream analyses ...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-47933 | biostudies-arrayexpress
UnknownNovel enhancers of guanylyl cyclase-A activity acting via allosteric modulation.
Not available
S-EPMC10952227 | biostudies-literature
ProteomicsDynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset in nemaline myopathy
Mansur A, Joseph R, Jean-Beltran PM, Udeshi ND, Pearce C, Jiang H, Iwase R, McNamara E, Widrick J, Perez C, Ravenscroft G, Cole PA, Carr SA, Gupta VA. 2022 Ubiquitin-proteasome system (UPS) dysfunction is associated with the pathology of a wide range of human diseases including myopathies and muscul...
ORGANISM(S): Danio Rerio (ncbitaxon:7955) 
2022-07-29 | MSV000090018 | MassIVE
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel
HER2-positive and HER2-negative samples are compared within this DASL Cancer Panel Platform Two-class comparison
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25231 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors Whole Genome DASL
HER2-positive and HER2-negative samples are compared within this Whole Genome Platform Two-class comparison
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25233 | biostudies-arrayexpress
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