Sort   by:  
 Page size 
UnknownDescriptive Genomic Analysis and Sequence Genotyping of the Two Papaya Species (Vasconcellea pubescens and Vasconcellea chilensis) Using GBS Tools.
A genotyping by sequencing (GBS) approach was used to analyze the organization of genetic diversity in V. pubescens and V. chilensis. GBS identified 4675 and 4451 SNPs/INDELs in two papaya species. The cultivated orchards of V. pubescens exhibited scarce genetic diversity and low but significant gen...
S-EPMC9414553 | biostudies-literature
UnknownDetection of balance in the elderly under the influence of stress (DEPIE): A cross-sectional study protocol.
Age-related changes increase frailty and vulnerability to stress in older adults, and stress has been linked to poorer balance and fall risk. However, the mechanisms by which emotional stress may contribute to falls remain unclear. This study explores whether: 1) emotional stressors lead to neuromus...
S-EPMC12843555 | biostudies-literature
UnknownObesity changes the human gut mycobiome.
The human intestine is home to a diverse range of bacterial and fungal species, forming an ecological community that contributes to normal physiology and disease susceptibility. Here, the fungal microbiota (mycobiome) in obese and non-obese subjects was characterized using Internal Transcribed Space...
S-EPMC4600977 | biostudies-literature
UnknownComprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models.
Mammalian SWI/SNF (SWitch/Sucrose Non-Fermentable) complexes are ATP-dependent chromatin remodelers whose subunits have emerged among the most frequently mutated genes in cancer. Studying SWI/SNF function in cancer cell line models has unveiled vulnerabilities in SWI/SNF-mutant tumors that can lead ...
S-EPMC7763689 | biostudies-literature
UnknownPulmonary imaging in coronavirus disease 2019 (COVID-19): a series of 140 Latin American children.

Background

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which resulted in the worldwide coronavirus disease 2019 (COVID-19) pandemic of 2020, has particularly affected Latin America.

Objective

The purpose of the study was to analyze the imaging findings of pulmona...
S-EPMC8012415 | biostudies-literature
UnknownNavigating from phenotypic screen to clinical candidate: selective targeting the NLRP3 inflammasome
The NLRP3 inflammasome plays a pivotal role in host defence and drives inflammation against microbial threats, crystals, and danger-associated molecular patterns (DAMPs). Dysregulation of NLRP3 activity is associated with various human diseases, making it an attractive therapeutic target. Patients w...
S-SCDT-10_1038-S44321-024-00181-4 | biostudies-other
UnknownInhibitory to non-inhibitory evolution of the ζ subunit of the F1FO-ATPase of Paracoccus denitrificans and α-proteobacteria as related to mitochondrial endosymbiosis.
Introduction: The ζ subunit is a potent inhibitor of the F1FO-ATPase of Paracoccus denitrificans (PdF1FO-ATPase) and related α-proteobacteria different from the other two canonical inhibitors of bacterial (ε) and mitochon...
S-EPMC10469736 | biostudies-literature
UnknownAcute Promyelocytic Leukemia: A Long-Term Retrospective Study in Mexico.

Background

The present retrospective study reviewed acute promyelocytic leukemia (APL) cases recorded in Mexico between January 2007 and January 2017. The primary objective of the study was to evaluate overall survival (OS) in Mexican patients with APL. Secondary objective was to evaluate th...
S-EPMC8110230 | biostudies-literature
UnknownCardiac troponin and COVID-19 severity: Results from BIOCOVID study.

Background

Myocardial injury is a common finding in COVID-19 strongly associated with severity. We analysed the prevalence and prognostic utility of myocardial injury, characterized by elevated cardiac troponin, in a large population of COVID-19 patients, and further evaluated separately the...
S-EPMC7995181 | biostudies-literature
UnknownPreexposure chemoprophylaxis for HIV prevention in men who have sex with men.

Background

Antiretroviral chemoprophylaxis before exposure is a promising approach for the prevention of human immunodeficiency virus (HIV) acquisition.

Methods

We randomly assigned 2499 HIV-seronegative men or transgender women who have sex with men to receive a combination of two or...
S-EPMC3079639 | biostudies-literature
Sort   by:  
 Page size