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Each tissue or cell line polyA+ RNA-labeled with Cy5 was hybridized against a common reference pool consisting of 11 different cell lines described elsewhere (Perou et al. 2000)
ORGANISM(S): Homo sapiens 
Gene amplifications and deletions frequently contribute to tumorigenesis. Characterization of these DNA copy-number changes is important for both the basic understanding of cancer and its diagnosis. Comparative genomic hybridization (CGH) was developed to survey DNA copy-number variations across a w...
ORGANISM(S): Homo sapiens 
Set of 65 surgical specimens of human breast tumors from 42 different individuals, using complementary DNA microarrays representing 8,102 human genes. Gene expression variation patterns within this set provided a distinctive molecular portrait of each tumor. Twenty of the tumors were sampled twice, ...
ORGANISM(S): Homo sapiens 
Fibroblast were isolated from either back or forearm punch biopsies taken by Dr. Kari Connolly(UCSF) from either normal control patients, patients with a diagnosis of Systemic Sclerosis with Diffuse Scleroderma and patients with a diagnosis of morphea. Scleroderma fibroblast were grown to confluenc...
ORGANISM(S): Homo sapiens 
Each tissue or cell line polyA+ RNA-labeled with Cy5 was hybridized against a common reference pool consisting of 11 different cell lines described elsewhere (Perou et al. 2000) Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Using regression cor...
ORGANISM(S): Homo sapiens 
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of coexpressed ge...
ORGANISM(S): Homo sapiens 
Fibroblast were isolated from either back or forearm punch biopsies taken by Dr. Kari Connolly(UCSF) from either normal control patients, patients with a diagnosis of Systemic Sclerosis with Diffuse Scleroderma and patients with a diagnosis of morphea. Scleroderma fibroblast were grown to confluenc...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE3886: Scleroderma Morphea Normal Fibroblasts GSE3887: Scleroderma Architecture Cell Lines Abstract: We used DNA microarrays representing >12,000 human genes to characterize gene expression patterns in skin biopsies from individuals wit...
ORGANISM(S): Homo sapiens 
The data from these cell lines is described in figure 2 of the mansucript "Systemic and cell-type specific gene expression patterns in scleroderam skin" by Whitfield et al. (2003) PNAS. Aortic smooth muscle cells and microvascular endothelial cells were obtained from Clonetics and culture...
ORGANISM(S): Homo sapiens 
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