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ProteomicsQuantitative proteomic analysis of oxaliplatin induced peripheral neurotoxicity
We performed a data independent acquisition (DIA) -based quantitative proteomics strategy to investigate the global proteome alteration in the dorsal root ganglion (DRG) tissues from mice injected with oxaliplatin for different periods.
ORGANISM(S): Mus musculus (Mouse) 
2022-07-11 | PXD031322 | Pride
Metabolism Peripheral neurotoxicity Oxaliplatin Ros Quantitative proteomics 
UnknownApproaches to measure paediatric chemotherapy-induced peripheral neurotoxicity: a systematic review.
Not available
S-EPMC8152573 | biostudies-literature
UnknownCurrent View in Platinum Drug Mechanisms of Peripheral Neurotoxicity.
Not available
S-EPMC5606682 | biostudies-literature
UnknownMolsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through soluble guanylyl cyclase activation.
Not available
S-EPMC11336221 | biostudies-literature
UnknownSusceptibility of different mouse strains to oxaliplatin peripheral neurotoxicity: Phenotypic and genotypic insights.
Not available
S-EPMC5636145 | biostudies-literature
ProteomicsA human iPSC-derived sensory neuron platform for high-throughput discovery of neuroprotectants against chemotherapy-induced peripheral neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect of cancer treatment, yet the lack of predictive human models has hindered therapeutic progress. We have established a scalable model of paclitaxel-induced axon degeneration and neurotoxicity in iPSC-derived sensor...
ORGANISM(S): Homo sapiens (Human) 
2026-04-03 | PXD074954 | Pride
Axon degeneration Ipsc-derived sensory neurons Ste20 kinases Neuroprotective small molecules High-throughput screening Chemotherapy-induced peripheral neuropathy 
UnknownPredictive Biomarkers of Oxaliplatin-Induced Peripheral Neurotoxicity.
Not available
S-EPMC8306803 | biostudies-literature
UnknownCombination of pathological, biochemical and behavioral evaluations for peripheral neurotoxicity assessment in isoniazid-treated rats.
Not available
S-EPMC10995436 | biostudies-literature
UnknownUpdates on Oxaliplatin-Induced Peripheral Neurotoxicity (OXAIPN).
Not available
S-EPMC5634688 | biostudies-literature
UnknownAn in vivo mechanism for the reduced peripheral neurotoxicity of NK105: a paclitaxel-incorporating polymeric micellar nanoparticle formulation.
Not available
S-EPMC5317268 | biostudies-literature
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