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ProteomicsMouse connective tissue mast cell proteome
Mast cells are hematopoietic cells that reside preferentially in tissues exposed to internal and external environments. Mast cells sense immunological, inflammatory and environmental stimuli, and can be activated to release granules and generate inflammatory mediators. Mast cell-derived products con...
ORGANISM(S): Mus musculus (Mouse) 
2020-02-12 | PXD015040 | Pride
Mouse Peritoneal mast cell Mast cell 
TranscriptomicsPeritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes
Transcriptome analysis of two population of peritoneal mononuclear phagocytes (CD14+ macrophages and CD1c+ dendritic cells) in peritoneal dialysis effluent from stable (infection-free) peritoneal dialysis patients.
ORGANISM(S): Homo sapiens 
2017-01-23 | E-MTAB-5439 | biostudies-arrayexpress
ProteomicsA Nerve and Mast Cell Sentinel System Releases Extracellular Condensates to Induce Macrophage Repair
The peritoneal cavity has a higher density of immune cells then does blood. These cells are primarily localized within the bulk flow of fluid. As such, any perturbation within the peritoneum, ranging from a sterile injury to endometriosis to ovarian cancer, requires that the immune cells find a way ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-17 | PXD061150 | Pride
Granules Mouse Mast cell 
TranscriptomicsTemporal gene expression profiling of myeloid cells during the peritoneal foreign body response
This study dermined the temporal gene expression profile of myeloid subpopulations recruited to the peritoneal cavity to encapsulate implanted foreign material. Sterile foreign objects were inserted into the peritoneal cavities of MacGreen mice (in which the Csf1r promoter directs myeloid-specific ...
ORGANISM(S): Mus musculus 
2014-09-17 | E-GEOD-53101 | biostudies-arrayexpress
TranscriptomicsRole of IL-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK) in mast cell response to lipopolysaccharide (LPS)
Mast cells are indispensable for LPS-induced septic hypothermia, in which TNF-α plays an essential role to initiate sepsis. Tec family non-receptor tyrosine kinases ITK and BTK regulate mast cell-derived TNF-α in response to allergic antigen, but their role in LPS-induced TNF-α production by mast...
ORGANISM(S): Mus musculus 
2015-11-23 | E-GEOD-64287 | biostudies-arrayexpress
GenomicsEx vivo analysis of gene expression in Roquin1/2 deficient peritoneal mast cells
Ex vivo analysis of gene expression in Roquin1/2 deficient peritoneal mast cells
PRJNA1249477 | ENA
TranscriptomicsCircadian transcriptional profiling of peritoneal macrophages
In the immune system various parameters and immune functions are controlled by the circadian system. To investigate molecular mechanisms that link the circadian clock and the immune system we analyzed the transcriptom of peritoneal macrophages from mice collected in a time course for two consecutive...
ORGANISM(S): Mus musculus 
2010-11-24 | E-GEOD-25585 | biostudies-arrayexpress
TranscriptomicsExpression data from isolated peritoneal macrophages treated with Histidine-rich glycoprotein
Histidine-rich glycoprotein (HRG) is a 75 kDa heparin-binding plasma protein which has been implicated in regulation of tumor angiogenesis and growth. To exert some of its biological functions, HRG acts on macrophages.This study was performed to assess changes in gene expression in peritoneal macrop...
ORGANISM(S): Mus musculus 
2011-12-06 | E-GEOD-34164 | biostudies-arrayexpress
TranscriptomicsTranscriptome changes in IL-10 treated peritoneal macrophages
To try to identify the mechanism of STAT3s indirect action we have used a genomic approach to map the binding sites of STAT3 within the genome and also used RNA-seq technology to map the changes in RNA expression and transcript isoform abundance in response to IL-10. Examination of transcriptome cha...
ORGANISM(S): Mus musculus 
2012-02-13 | E-GEOD-31530 | biostudies-arrayexpress
TranscriptomicsGene expression profile prospectively predicts peritoneal relapse after curative surgery of gastric cancer
Purpose: Our study aimed to disclose the specific gene expression profile representing peritoneal relapses inherent in primary gastric cancers and to identify patients at high risk of peritoneal relapse in a prospective study on the basis of the molecular prediction. Experimental Design: RNA samples...
ORGANISM(S): Homo sapiens 
2010-05-23 | E-GEOD-15081 | biostudies-arrayexpress
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