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Changes in the rate and fidelity of mitochondrial protein synthesis impact the metabolic and physiological roles of mitochondria. Here we explored how environmental stress in the form of a high-fat diet modulates mitochondrial translation using mutant mice with error-prone (Mrps12ep/ep) or hyper-acc...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024633 | Pride
Mutations in the TANGO2 gene cause an autosomal recessive disorder characterised by developmental delay, stress-induced episodic rhabdomyolysis, and cardiac arrhythmias along with severe metabolic crises. Although TANGO2 mutations result in a well characterised disease pathology, the function of TAN...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-04-22 | PXD056037 | Pride
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