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UnknownImpact of the addition of carboplatin and/or bevacizumab to neoadjuvant once-per-week paclitaxel followed by dose-dense doxorubicin and cyclophosphamide on pathologic complete response rates in stage II to III triple-negative breast cancer: CALGB 40603 (Alliance).
Not available
S-EPMC4268249 | biostudies-literature
TranscriptomicsHigh Reproducibility Using Sodium Hydroxide Stripped Long Oligonucleotide DNA Microarrays
Recently, long oligonucleotide (60-70mer) microarrays for two-color experiments have been developed and are gaining widespread use. In addition, when there is limited availability of mRNA from tissue sources, RNA amplification can and is being used to produce sufficient quantities of cRNA for microa...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-1706 | biostudies-arrayexpress
TranscriptomicsClinical and Pathologic Response of the Primary Tumor in Women Receiving Neoadjuvant Docetaxel-Capecitabine (+/- Trastuzumab) Chemotherapy
Results: In subjects who completed treatment and surgery, the pCR and near-complete response rates were 15.8% in HER2-negative and 50% in HER2-positive subjects. When stratified by genomic subtype, subjects of the HER2-enriched subtype had the best response (66.7%), the luminal A (11%) and B (4.8%) ...
ORGANISM(S): Homo sapiens 
2011-03-18 | E-GEOD-22358 | biostudies-arrayexpress
TranscriptomicsComparison of Poly(A) capture versus Ribosomal RNA depletion methods for RNA-seq
Methods: RNA-sequencing was performed on matched samples obtained across several different gene expression measurement methods including: (a) fresh-frozen (FF) RNA samples by mRNA-seq, Ribo-zero and DSN and (b) FFPE samples by Ribo-zero and DSN. We also assayed the matched samples with Agilent micro...
ORGANISM(S): Homo sapiens 
2014-08-20 | E-GEOD-51783 | biostudies-arrayexpress
UnknownPrognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer.
Not available
S-EPMC3532392 | biostudies-literature
TranscriptomicsMPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary tumors with different hormonal requirements
Introduction: Over the past several years, we have been interested in understanding the mechanisms by which hormone-dependent (HD) mammary carcinomas grow in the absence of the stimulatory hormone. We have hypothesized that the stromal compartment plays a pivotal role in the acquisition of the hormo...
ORGANISM(S): Mus musculus 
2011-01-22 | E-GEOD-23214 | biostudies-arrayexpress
TranscriptomicsLoss of the retinoblastoma tumor suppressor is a common event in Basal-like and Luminal B breast carcinomas
Breast cancers can be classified using whole genome expression into distinct subtypes that show differences in patient prognosis. One of these groups, the basal-like carcinomas, are poorly differentiated, highly metastatic, and genomically unstable. These tumors also contain specific genetic alter...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-10884 | biostudies-arrayexpress
UnknownTBCRC 001: randomized phase II study of cetuximab in combination with carboplatin in stage IV triple-negative breast cancer.
Not available
S-EPMC3413275 | biostudies-literature
TranscriptomicsCell state transitions regulated by Slug are critical for tissue regeneration and tumor initiation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-06-23 | E-GEOD-54735 | biostudies-arrayexpress
TranscriptomicsMicroarray Coverage of Universal Human Reference RNA on microarrays with yeast controls
Microarray coverage of UHRR was determined by counting the number of spots with intensities exceeding the 1% and 5% false positive rates defined using the yeast negative control spots. Seven microarrays from different print runs were used. In four experiments, the UHRR was labeled with Cy5 and in th...
ORGANISM(S): Homo sapiens 
2006-01-04 | E-GEOD-3973 | biostudies-arrayexpress
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