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MetabolomicsSequential lipidomic, metabolomic, and proteomic analyses of serum, liver, and heart tissue specimens from peroxisomal biogenesis factor 11α knockout mice
Peroxisomes are versatile single membrane-enclosed cytoplasmic organelles, involved in reactive oxygen species (ROS) and lipid metabolism and diverse other metabolic processes. Peroxisomal disorders result from mutations in Pex genes-encoded proteins named peroxins (PEX proteins) and single peroxiso...
2022-02-02 | MTBLS1887 | MetaboLights
ProteomicsPex39 facilitates peroxisomal import of PTS2 proteins – PEX39 KO SILAC data
Peroxisomes are metabolic organelles essential for human health. Defects in peroxisomal biogenesis proteins (peroxins/PEXs) cause devastating disease. PEX7 binds cargo proteins containing a type 2 peroxisomal targeting sequence (PTS2) to enable import of PTS2 proteins from the cytosol into peroxisom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-07-07 | PXD051550 | Pride
Quantitative mass spectrometry Peroxisomes Silac Saccharomyces cerevisiae Peroxisomal matrix protein import Pts2 import Pex39 
ProteomicsPex39 facilitates peroxisomal import of PTS2 proteins – ScPex18 AP-MS data
Peroxisomes are metabolic organelles essential for human health. Defects in peroxisomal biogenesis proteins (peroxins/PEXs) cause devastating disease. PEX7 binds cargo proteins containing a type 2 peroxisomal targeting sequence (PTS2) to enable import of PTS2 proteins from the cytosol into peroxisom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-07-07 | PXD051501 | Pride
Peroxisomes Affinity purification-mass spectrometry Label free quantification Saccharomyces cerevisiae Peroxisomal matrix protein import Pts2 import Pex39 
GenomicsPeroxisomal retrograde signaling in C. elegans
Peroxisomal retrograde signaling in C. elegans
PRJNA657442 | ENA
ProteomicsPhosphorylation of the receptor protein Pex5p modulates import of PTS1 cargoes into peroxisomesPhosphorylation of the receptor protein Pex5p modulates import of PTS1 cargoes into peroxisomes
Peroxisomes are dynamic organelles with vital functions in cellular metabolism and dysfunction of peroxisomes is associated with human diseases. To fulfill their multiple roles, peroxisomes rely on import of nuclear-encoded matrix proteins, most carrying a peroxisomal targeting signal (PTS) 1. The r...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-10 | PXD015676 | Pride
Phosphoproteomics Peroxisomal protein import Pex5p Phosphorylation 
UnknownPEX39 facilitates the peroxisomal import of PTS2-containing proteins.
Not available
S-EPMC12339391 | biostudies-literature
UnknownTowards designer organelles by subverting the peroxisomal import pathway.
Not available
S-EPMC5587766 | biostudies-literature
UnknownPeroxisomal import stress activates integrated stress response and inhibits ribosome biogenesis.
Not available
S-EPMC11470064 | biostudies-literature
UnknownMitotic phosphorylation of Pex14p regulates peroxisomal import machinery.
Not available
S-EPMC7659713 | biostudies-literature
TranscriptomicsPeroxisomal retrograde signaling in C. elegans
Distinct retrograde signaling pathways have been identified for several cellular organelles. These pathways are important to maintain the function of these organelles in response to organelle-specific stress. Using Caenorhabditis elegans, we show for the first time that such a retrograde signaling a...
ORGANISM(S): Caenorhabditis elegans 
2020-12-19 | GSE156318 | GEO
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