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This study investigates metabolomic changes associated with personalized cancer therapy responses in patient-derived organoid chips containing a reconstructed tumor microenvironment. The dataset includes de-identified sample metadata, raw mass spectrometry files, processed metabolite abundance ma...

2026-08-06 | MTBLS15195 | MetaboLights

The human immune system has evolved to interact with various commensal and pathogenic bacteria in intricate and nuanced ways. While the diversity of bacteria presents fundamental challenges in understanding immune-microbe interactions, it also offers ample opportunities for developing effective i...

2025-07-01 | MTBLS12666 | MetaboLights
Predicting Outcomes of Prostate Cancer Immunotherapyby Personalized Mathematical Models Natalie Kronik1¤, Yuri Kogan1, Moran Elishmereni1, Karin Halevi-Tobias1, Stanimir Vuk-Pavlovic ́2.,Zvia Agur1*.1Institute for Medical BioMathematics, Bene Ataroth, Israel,2College of Medicine, Mayo Clinic, Roche...
2020-01-13 | MODEL2001130003 | BioModels
This QSP model explains how the mechanism of action connects to the clinical outcomes and, therefore, may serve as an important model-based platform to guide the development and personalized dosing of the CART therapy.
2025-01-15 | MODEL2009230001 | BioModels
Human iPSC-based personalized cell therapy of PD
Human iPSC-based personalized cell therapy of PD
Precision Phenomics to Personalized Drug Therapy (P3DT)
Precision Phenomics to Personalized Drug Therapy (P3DT)
The Drosophila gene dLmo encodes a transcriptional regulator involved in wing development and behavioral responses to cocaine and ethanol. We were interested in discovering novel transcriptional targets of dLmo in the nervous system by examining gene expression changes in the heads of wild-type flie...
ORGANISM(S): Drosophila melanogaster 
Rosuvastatin is a quite known lipid-lowering agent generally used for hypercholesterolemia treatment and coronary artery diseases prevention. There is substantial inter-individual variability in the absorption of statins usually caused by genetic polymorphisms leading to variation in the correspondi...
2021-10-29 | MTBLS3128 | MetaboLights
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