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TranscriptomicsPersistent Organic Pollutants cause insulin resistance and ruin the health effects of salmon oil
Transcriptional profiling of Rat liver submitted to high fat diets made with either crude (HFC) or refined salmon oil (HFR). Keywords: transcriptomic analysis Two groups of rats were submitted to high fat diet containing either crude salmon oil (HFC) or refined salmon oil (HFR). After 28 days, liv...
ORGANISM(S): Rattus norvegicus 
2010-05-19 | E-GEOD-13716 | biostudies-arrayexpress
TranscriptomicsLoss of tight junction integrity induces loss of epithelial phenotype: case of Claudin11 knock out in testis.
Epithelium barrier integrity is assumed at least in part by the presence of junctions between cells. Tight-junction formation may be necessary for Sertoli cells to cease dividing and to support germ cell development. Microarray analysis of P20 Cldn11 +/- and Cldn11-/- testes confirmed the impact od ...
ORGANISM(S): Mus musculus 
2010-04-11 | E-GEOD-15492 | biostudies-arrayexpress
TranscriptomicsFTO: gene expression and function in skeletal muscle
We identified the target genes of FTO ("fat mass and obesity associated") in primary cultures of human skeletal muscle cells using adenoviral vectors expressing FTO or GFP and oligonucleotide microarrays. Human myotubes were prepared from 4 different skeletal muscle biopsies. After differe...
ORGANISM(S): Homo sapiens 
2011-07-05 | E-GEOD-22857 | biostudies-arrayexpress
TranscriptomicsPolyphenols protection against fructose overload
To decipher the beneficial effects of Polyphenols on health, healthy volunteers were randomized into two groups and were submitted to either a red grape polyphenol rich extract supplemented diet (PP) or a placebo diet (PCB) during 8 weeks. Then they were submitted to a fructose load (3g/kg Fat Free ...
ORGANISM(S): Homo sapiens 
2013-02-04 | E-GEOD-35764 | biostudies-arrayexpress
TranscriptomicsGene regulation by full length human adiponectin
Transcriptionnal profiling of 4 human cell lines treated during 3 hours with human adiponectin Keywords: transcriptionnal analysis Four human cell lines (Hela, HepG2, Panc-1, Hek293) were grown until confluence. These cell lines were serum depleted during 2 hours and then treated with human adipone...
ORGANISM(S): Homo sapiens 
2010-12-09 | E-GEOD-14070 | biostudies-arrayexpress
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