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UnknownIntracellular zinc protects tumours from T cell-mediated cytotoxicity.
Not available
S-EPMC11618339 | biostudies-literature
UnknownLinear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis.
Not available
S-EPMC5120208 | biostudies-literature
UnknownEspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.
Not available
S-EPMC7613272 | biostudies-literature
TranscriptomicsRNA-seq of murine small intestinal organoids treated with type I PRMT inhibitor MS023 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 5µM inhibitor MS023 (PubChem CID 92136227), which targets type I protein arginine methyltransferases Prmt1, Prmt3, Prmt4, Prmt6, Prmt8. Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), medi...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9291 | biostudies-arrayexpress
TranscriptomicsCombinatory microarray and SuperSAGE analyses identify pairing-dependently transcribed genes in Schistosoma mansoni males, such as follistatin [Microarray]
Transcriptional profiling of S. mansoni pairing-experienced males (EM) vs. pairing unexperienced males (UM) Two conditions (EM vs. UM) with three biological samples of EM and in parallel other three biological samples of UM. For each sample (three EM and three UM) were performed four technical rep...
ORGANISM(S): Schistosoma mansoni 
2013-09-09 | E-GEOD-44193 | biostudies-arrayexpress
TranscriptomicsAgilent data from Arabidopsis thaliana enriched guard cell tissue and leafs.
To identify genes of the guard cell transcriptome of Arabidopsis thaliana enriched guard cell samples were compared with total leaf tissue. Genes of the abscisic acid and humidity response of Arabidopsis thaliana guard cells were identified by treatment with ABA-Spray and low humidity. total samples...
ORGANISM(S): Arabidopsis thaliana 
2013-01-14 | E-GEOD-41054 | biostudies-arrayexpress
UnknownCellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus.
Not available
S-EPMC4426461 | biostudies-literature
TranscriptomicsRNA-seq of murine small intestinal organoids treated with Ep300/Crebbp inhibitor I-CBP112 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 3µM inhibitor I-CBP112 (PubChem CID 90488984), which targets E1A Binding Protein P300 (Ep300) and Creb-binding protein (Crebbp, Cbp). Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), media ...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9290 | biostudies-arrayexpress
TranscriptomicsThe nucleosome remodeler SNF2L modulates WNT signaling for cellular homeostasis
ISWI is an evolutionary conserved ATPase that catalyzes nucleosome remodeling in several different complexes. Two mammalian ISWI orthologs, SNF2H and SNF2L, have specialized functions despite their high similarity. Due to the lack of reagents the functions of SN2L in human cells had not been establi...
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-30471 | biostudies-arrayexpress
TranscriptomicsValproic acid achieves its anticancer activity by re-expression of cyclin D2
In this study we could show that the treatment of primary murine prostate cancer(PCa) cells derived from the well-established TRAMP (transgenic adenocarcinoma ofmouse prostate) model with the histone deacetylase inhibitor (HDI) valproic acid (VPA) has an anti-proliferative, anti-migrative and anti-i...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-34072 | biostudies-arrayexpress
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