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MetabolomicsWhat CHO is made of: Variations in the biomass composition of Chinese hamster ovary cell lines

Background: Cell line specific, genome-scale metabolic models enable rigorous and systematic in silico investigation of cellular metabolism. Such models have recently become available for Chinese hamster ovary (CHO) too. However, a key ingredient, namely an experimentally validat...

2020-07-13 | MTBLS1210 | MetaboLights
ProteomicsProteome analyses reveal ER stress-induced changes in protein abundance associated with Ube2j2 deficiency in human cell culture
The unfolded protein response (UPR) helps reinstate cellular proteostasis upon an accumulation of misfolded proteins in the endoplasmic reticulum (ER), in part through ER-associated degradation (ERAD). Ube2j2 is an ER-localized E2 ubiquitin-conjugating enzyme that participates in ERAD. We used mass ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-09 | PXD076153 | Pride
Erad Ubiquitin proteasome system Unfolded protein response Protein degradation Ube2j2 E2 conjugating enzyme 
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