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ProteomicsUBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice
For proteomics analysis, testes of Ube2j2-/- and WT mice were collected on ice, washed once with pre-cooled PBS, dried with absorbent paper, and immediately placed in liquid nitrogen, dry ice, or at -80 ℃. Samples were packed in dry ice and transported to Hangzhou Jingjie Biotechnology Company (PTM ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-05 | PXD063637 | Pride
Meiosis arrest Synaptonemal complex disassembly. Ube2j2 Homologous recombination 
UnknownUBE2J2 sensitizes the ERAD ubiquitination cascade to changes in membrane lipid saturation.
Not available
S-EPMC12511567 | biostudies-literature
UnknownUBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice.
Not available
S-EPMC12275893 | biostudies-literature
ProteomicsProteome analyses reveal ER stress-induced changes in protein abundance associated with Ube2j2 deficiency in human cell culture
The unfolded protein response (UPR) helps reinstate cellular proteostasis upon an accumulation of misfolded proteins in the endoplasmic reticulum (ER), in part through ER-associated degradation (ERAD). Ube2j2 is an ER-localized E2 ubiquitin-conjugating enzyme that participates in ERAD. We used mass ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-09 | PXD076153 | Pride
Erad Ubiquitin proteasome system Unfolded protein response Protein degradation Ube2j2 E2 conjugating enzyme 
ProteomicsProteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (UBE2I, UBE2J1, UBE2J2, UBE2K).
The project goal is to identify the proteins that are regulated with loss of the E2 enzymes. In this study UBE2I, UBE2J1, UBE2J2, UBE2K were knocked down.
ORGANISM(S): Homo sapiens (Human) 
2023-11-14 | PXD042333 | Pride
Uba1  e2 ubiquitin-conjugating enzymes  ubiquitin  human cells 
ProteomicsProteomic analysis of 3T3 murine fibroblast used as feeder-layer
The unfolded protein response (UPR) helps reinstate cellular proteostasis upon an accumulation of misfolded proteins in the endoplasmic reticulum (ER), in part through ER-associated degradation (ERAD). Ube2j2 is an ER-localized E2 ubiquitin-conjugating enzyme that participates in ERAD. We used mass ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-03 | PXD078047 | Pride
Feeder-layer Fibroblast Skin expansion 
UnknownDeterminants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes.
Not available
S-EPMC11649903 | biostudies-literature
UnknownThe role of ubiquitin-conjugating enzyme Ube2j1 phosphorylation and its degradation by proteasome during endoplasmic stress recovery.
Not available
S-EPMC5559397 | biostudies-literature
UnknownIdentification and characterization of putative biomarkers and therapeutic axis in Glioblastoma multiforme microenvironment.
Not available
S-EPMC10395518 | biostudies-literature
ProteomicsProteomic profiling identifies key proteins, pathways and molecular subtypes regulating chemo-radio-sensitivity and relapse in rhabdomyosarcoma
Rhabdomyosarcoma (RMS), the most common pediatric soft tissue sarcoma, exhibits marked clinical heterogeneity driven by poorly understood molecular mechanisms. Identifying the molecular characteristics of different RMS subtypes and the molecular pathways influencing RMS treatment response and recurr...
ORGANISM(S): Homo Sapiens 
PXD069421 |
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