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TranscriptomicsEpigenetic profiling in CD4 and CD8 T cells from Graves disease patients reveals changes in genes associated with T cell receptor signaling
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-06 | E-GEOD-71957 | biostudies-arrayexpress
TranscriptomicsEpigenetic profiling in CD4 and CD8 T cells from Graves’ disease patients reveals changes in genes associated with T cell receptor signaling [methylation]
In Graves’ disease (GD), a combination of genetic, epigenetic and environmental factors causes an autoimmune response to the thyroid gland, characterized by lymphocytic infiltrations and autoantibodies targeting the thyroid stimulating hormone receptor (TSHR) and other thyroid antigens. To identif...
ORGANISM(S): Homo sapiens 
2015-11-06 | E-GEOD-71955 | biostudies-arrayexpress
TranscriptomicsEpigenetic profiling in CD4 and CD8 T cells from Graves’ disease patients reveals changes in genes associated with T cell receptor signaling [gene expression]
In Graves’ disease (GD), a combination of genetic, epigenetic and environmental factors causes an autoimmune response to the thyroid gland, characterized by lymphocytic infiltrations and autoantibodies targeting the thyroid stimulating hormone receptor (TSHR) and other thyroid antigens. To identif...
ORGANISM(S): Homo sapiens 
2015-11-06 | E-GEOD-71956 | biostudies-arrayexpress
GenomicsEpigenetic profiling in CD4 and CD8 T cells from Gravesâ?? disease patients reveals changes in genes associated with T cell receptor signaling [ChIP-seq]
In Gravesâ?? disease (GD), a combination of genetic, epigenetic and environmental factors causes an autoimmune response to the thyroid gland, characterized by lymphocytic infiltrations and autoantibodies targeting the thyroid stimulating hormone receptor (TSHR) and other thyroid antigens. To identif...
ORGANISM(S): Homo sapiens 
2015-11-06 | E-GEOD-71952 | biostudies-arrayexpress
TranscriptomicsHEK293 stably expressing Autoimmune regulator protein
Auto Immune REgulator (AIRE) protein expression in HEK293 cells Three cell-lines where used in the study: HEK293-NC; control cell-line expressing yellow fluorescent protein (YFP) HEK-AIRE1, HEK-AIRE2; two different clone-derived Autoimmune regulator protein expressing cell-lines HEK-AIRE-D312A; c...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-16877 | biostudies-arrayexpress
TranscriptomicsPeptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence
The induction of genetic competence is a strategy used by bacteria to increase their genetic repertoire under stressful environmental conditions. Recently, Streptococcus pneumoniae has been shown to co-ordinate the uptake of transforming DNA with fratricide via increased expression of the peptide ph...
ORGANISM(S): Streptococcus mutans UA159 
2010-05-29 | E-GEOD-22019 | biostudies-arrayexpress
UnknownAssociation Between Extending CareFirst's Medical Home Program to Medicare Patients and Quality of Care, Utilization, and Spending.
Not available
S-EPMC5710572 | biostudies-literature
TranscriptomicsBacillus_anthracis_CGH
Analysis of genomic content of closely related Bacillus species. Refer to individual records for strain information. Refer to platform and individual sample records for experimental protocols.
ORGANISM(S): Bacillus anthracis 
2010-06-05 | E-GEOD-341 | biostudies-arrayexpress
UnknownVisuospatial functioning is associated with sleep disturbance and hallucinations in nondemented patients with Parkinson's disease.
Not available
S-EPMC6681669 | biostudies-literature
UnknownLoss of enigma homolog protein results in dilated cardiomyopathy.
Not available
S-EPMC3684396 | biostudies-literature
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