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UnknownscPanel: a tool for automatic identification of sparse gene panels for generalizable patient classification using scRNA-seq datasets.
Not available
S-EPMC11442147 | biostudies-literature
TranscriptomicsWnt addiction of genetically defined cancers reversed by PORCN inhibition
Enhanced sensitivity to Wnts is an emerging hallmark of a subset of cancers, defined in part by mutations regulating the abundance of their receptors. Inhibition of Wnt secretion by blocking an essential post-translational modification, palmitoleation, provides a useful therapeutic intervention. Inh...
ORGANISM(S): Homo sapiens 
2015-08-12 | E-GEOD-69687 | biostudies-arrayexpress
Transcriptomicsrat_brain_mRNASeq
mRNA Sequencing was done in whole brain hemispheres of the 75 most tame and 75 most aggressive rats of an F2 intercross of rat lines selected for tame and aggressive behavior towards humans. The brain gene expression levels are associated with 1728 genetic markers across the genome to identify expr...
ORGANISM(S): Rattus norvegicus 
2014-08-27 | E-MTAB-2544 | biostudies-arrayexpress
ProteomicsProteome profiling of an isogenic CAG allelic panel of Huntington disease hESCs and NPCs
Whole proteome profiling and quantification was performed on an isogenic Huntington disease (IsoHD) human embryonic stem cell (hESC) allelic panel. The IsoHD hESCs harbour 30, 45, 65 and 81 CAG repeats in the first exon of HTT. Whole proteome quantification was also performed on neural progenitor ce...
ORGANISM(S): Homo Sapiens (human) 
2019-02-14 | PXD006585 | JPOST Repository
TranscriptomicsTranscription profiling of peritoneal fat of SHR/01a (spontaneously hypertensive rat), BN-Lx (Brown Norway congenic carrying polydactyly-luxate syndrome)and recombinant inbred (HXB/BXH) 6-week old rat strains
Gene expression profiling of peritoneal fat of SHR/01a (spontaneously hypertensive rat), BN-Lx (Brown Norway congenic carrying polydactyly-luxate syndrome)and recombinant inbred (HXB/BXH) 6-week old rat strains.
ORGANISM(S): Rattus norvegicus 
2010-11-18 | E-AFMX-7 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse heart implicatesosteoglycin (Ogn) in the regulation of left ventricular mass
Left ventricular mass (LVM) and cardiac gene expression are complex traits regulated by factors both intrinsic and extrinsic to the heart. To dissect the major determinants of LVM, we combined expression quantitative trait locus1 and quantitative trait transcript (QTT) analyses of the cardiac transc...
ORGANISM(S): Homo sapiens 
2008-11-15 | E-GEOD-10161 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat liver from recombinant inbred strains derived from BN and SHR rats
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2011-07-12 | E-MTAB-323 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat aorta from recombinant inbred strains derived from BN and SHR rats
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2011-07-12 | E-MTAB-322 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle tissue from spontaneously hypertensive rats and normotensive rats in a set of recombinant inbred strains
We aimed to identify gene expression profiles/differences between spontaneously hypertensive rat(SHR) and normotensive rat (BN) in a set of recombinant inbred (RI) strains.
ORGANISM(S): Rattus norvegicus 
2008-04-15 | E-TABM-458 | biostudies-arrayexpress
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