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TranscriptomicsTranscription profiling by array of mice with diet-induced obesity treated with a locked-nucleic-acid-modified oligonucleotide (LNA-antimiR) which antagonises liver-expressed miR-122
Effect of miR-122 silencing in diet induced obese mice.
ORGANISM(S): Mus musculus 
2008-03-27 | E-MEXP-1406 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from Pan troglodytes with chronic hepatitis C virus infection following therapeutic silencing of microRNA-122 using SPC3649
Chimpanzees with chronic Hepatitis C infection treated with LNA-antimiR-122.
ORGANISM(S): Pan troglodytes 
2010-10-01 | E-MEXP-2375 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of dorsal pancreas tissue from Ngn3 null mice and wild-type littermates at days 13 and 15 of embryonic development
This experiment was designed to analyze the expression of genes in dorsal pancreatic cells at two temporally separated stages of pancreas development. This was accomplished by comparing expression profiles of embryonic dorsal pancreas tissue from Ngn3 null mice with wild-type littermates at days 13...
ORGANISM(S): Mus musculus 
2007-07-17 | E-CBIL-31 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse pancreas development in NMRI embryos on consecutive days from e12.5 to e16.5
Development of the pancreas from the endoderm is initiated at embryonic day 9 of mouse development and over the following days several different cell types develop from pancreas progenitor cells. A distinct phase of pancreas development, known as the secondary transition, is initiated at day 13 of d...
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-8070 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver after silencing of microRNAs by seed-targeting tiny LNAs - in vivo antimiR-122
c57BL/6J female mice treated with LNA-antimiR's against miR-122.
ORGANISM(S): Mus musculus 
2011-07-05 | E-MEXP-2802 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver after silencing of microRNAs by seed-targeting tiny LNAs - in vivo antilet7
NMRI female mice treated with seed targeting LNA-antimiRs against the let-7 family.
ORGANISM(S): Mus musculus 
2011-07-05 | E-MEXP-2801 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa cells after silencing of microRNAs by seed-targeting tiny LNAs - in vitro antimiR-21
HeLa cells transfected with LNA-antimiR's against miR-21.
ORGANISM(S): Homo sapiens 
2011-07-05 | E-MEXP-2803 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human PC3 cells after silencing of microRNAs by seed-targeting tiny LNAs - in vitro antilet-7
PC3 cells transfected with LNA-antimiR's against let-7.
ORGANISM(S): Homo sapiens 
2011-07-05 | E-MEXP-2804 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human IFN-Gamma treated keratinocytes
An experiment comparing control versus IFN-g treated skin cells (one design factor on two levels). To evaluate the biological and the experimental variability, the following experimental design was planned as shown in Figure 1: "Control" and "IFN-g stimulated" keratinocytes were cultured in triplica...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1132 | biostudies-arrayexpress
TranscriptomicsLong noncoding RNA expression during human B-cell development
Long noncoding RNAs (lncRNAs) have emerged as important regulators of diverse cellular processes, but their roles in the developing immune system are poorly understood. In this study, we analysed lncRNA expression during human B-cell development by array-based expression profiling of eleven distinct...
ORGANISM(S): Homo sapiens 
2016-02-09 | E-GEOD-69033 | biostudies-arrayexpress
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