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Down syndrome (DS) is a genetic condition where the person is born with an extra chromosome 21. DS is associated with accelerated aging; people with DS are prone to age-related neurological conditions including an early-onset Alzheimer’s disease. Using the Dp(17)3Yey/ + mice, which overexpresses a p...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-30 | PXD048079 | Pride
Background & AimsBarrett’s esophagus (BE), a metaplastic transformation driven by gastroesophageal reflux disease (GERD), induces oxidative stress but the underlying redox mechanisms remain poorly understood. Protein persulfidation (PSSH), a redox-sensitive, reversible, and antioxidative post-transl...
ORGANISM(S): Homo sapiens (Human) 
2026-06-02 | PXD047338 | Pride
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