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ProteomicsHepatocyte Proteome Destabilization and Novel Targets for PFASs Unveiled through Combined Thermal Proteome Profiling and Deep Transfer Learning
TPP-CCR (Thermal proteome profiling with compound concentration range TPP-CCR) identified key protein targets for three representative PFASs and a benchmark sample of staurosporine.
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD059666 | Pride
ProteomicsOccurrence and fate of per/polyfluoroalkyl substances (PFASs) in residential wastewater treated with nitrogen-removing biofilters
Onsite wastewater treatment systems (OWTSs) are designed for the removal of pathogens and nutrients from septic effluent. However, many other contaminants are widespread in wastewater, including pharmaceuticals, personal care products, and other trace organic chemicals. We analyzed per/polyfluoroalk...
ORGANISM(S): Na 
2025-05-21 | MSV000097952 | MassIVE
TranscriptomicsUnveiling the molecular effects of replacement and legacy PFASs: Transcriptomic analysis of zebrafish embryos reveals surprising similarities and potencies
The prevalence of per- and poly fluoroalkyl substances (PFASs) in the environment has prompted restrictions on legacy PFASs due to their recognized toxic effects. Consequently, alternative “replacement” PFASs have been introduced and are prevalent in environmental matrices. Few studies have investig...
ORGANISM(S): Danio rerio 
2024-06-30 | GSE263667 | GEO
UnknownFreshwater ecotoxicity characterization factors for PFASs.
Not available
S-EPMC11984296 | biostudies-literature
UnknownOccurrence, Sources, and Prioritization of Per- and Polyfluoroalkyl Substances (PFASs) in Drinking Water from Yangtze River Delta, China: Focusing on Emerging PFASs.
Not available
S-EPMC12155778 | biostudies-literature
ProteomicsA Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances
Poly- and perfluoroalkyl substances (PFASs) are widely used in industrial products and consumer goods. Due to their extreme-ly recalcitrant nature and potential bioaccumulation and toxicity, exposure to PFASs may result in adverse health outcomes in humans and wildlife. In this study, we developed a...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD025757 | Pride
Pfass Probe 
GenomicsUnveiling the molecular effects of replacement and legacy PFASs: Transcriptomic analysis of zebrafish embryos reveals surprising similarities and potencies
Unveiling the molecular effects of replacement and legacy PFASs: Transcriptomic analysis of zebrafish embryos reveals surprising similarities and potencies
PRJNA1098727 | ENA
UnknownPerfluoroalkyl Substances (PFASs) in the Canadian Freshwater Environment.
Not available
S-EPMC9079020 | biostudies-literature
Genomics
Mouse liver transcriptome exposed to PFASs
PRJNA674778 | ENA
UnknownCharacterizing PFASs in aquatic ecosystems with 3D hydrodynamic and water quality models.
Not available
S-EPMC11381888 | biostudies-literature
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