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ProteomicsThe augmin complex architecture reveals structural insights into microtubule branching
In mitosis, the augmin complex binds to spindle microtubules to recruit the γ-tubulin ring complex (γ-TuRC), the principal microtubule nucleator, for the formation of branched microtubules. Our understanding of augmin-mediated microtubule branching is strongly hampered by the lack of structural info...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-10-13 | PXD034895 | Pride
Microtubule Augmin Nucleation Cell cycle Branching 
TranscriptomicsHistone deacetylase inhibition replicates aspects of the adaptive response to exercise and improves muscle metabolism and cardiac function in obesity.
Drugs used to treat obesity and type 2 diabetes have limited efficacy in directly normalising muscle metabolism. The discovery of molecules mediating exercise adaptations, and drugs that modulate their activity, is a potential strategy to address this therapeutic gap. Here we show that genetic impai...
ORGANISM(S): Mus musculus 
2015-01-28 | E-GEOD-54642 | biostudies-arrayexpress
UnknownEffects of dapagliflozin on mortality in patients with chronic kidney disease: a pre-specified analysis from the DAPA-CKD randomized controlled trial.
Not available
S-EPMC8244648 | biostudies-literature
UnknownScreening policies, preventive measures and in-hospital infection of COVID-19 in global surgical practices.
Not available
S-EPMC7567431 | biostudies-literature
UnknownImpact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic.
Not available
S-EPMC7929295 | biostudies-literature
UnknownSurgeons' fear of getting infected by COVID19: A global survey.
Not available
S-EPMC7461173 | biostudies-literature
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