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TranscriptomicsStarvation and chemotherapy
Tumor chemoresistance is often associated to high aerobic glycolysis rates and reduced oxidative phosphorylation by cancer cells, a phenomenon called the “Warburg effect”. Thus, a treatment reversing the Warburg effect could decrease tumor cell survival both in the presence or absence of chemothera...
ORGANISM(S): Mus musculus 
2015-08-11 | E-GEOD-60653 | biostudies-arrayexpress
TranscriptomicsIdentification of a New Cell Population Constitutively Circulating in Healthy Conditions and Endowed with a Homing Ability Toward Injured Sites
Stem and progenitor cells are the critical units for tissue maintenance, regeneration, and repair. The activation of regenerative events in response to tissue injury has been correlated with mobilization of tissue-resident progenitor cells, which is functional to the wound healing process. However, ...
ORGANISM(S): Mus musculus 
2015-12-04 | E-GEOD-64835 | biostudies-arrayexpress
MetabolomicsMaslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming
Chemoprevention is a pragmatic approach to reduce the risk of colorectal cancer, one of the leading causes of cancer-related death in western countries. In this regard, maslinic acid (MA), a pentacyclic triterpene extracted from wax-like coatings of olives, is known to inhibit proliferation and indu...
2017-02-09 | MTBLS240 | MetaboLights
TranscriptomicsSyntenin-1 is expressed in uveal melanoma and correlates with metastatic progression
Uveal melanoma is an aggressive cancer that metastasizes to the liver in about half of patients, being at that time almost always fatal. Identification of patients at high risk of metastases may provide indication for a frequent follow-up for early detection of metastases and treatment. The analysis...
ORGANISM(S): Homo sapiens 
2012-04-17 | E-GEOD-27831 | biostudies-arrayexpress
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