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Proteomics2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction
Mitochondria play a crucial role in regulating cellular homeostasis in response to intrinsic and extrinsic cues by changing cellular metabolism to meet these challenges. However, the molecular underpinnings of this regulation and the complete spectrum of these physiological outcomes remain largely u...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD064288 | Pride
Nuclear softening Brown adipose tissue Mitochondria 2-hydroxyglutarate 
TranscriptomicsTranscriptional profiles of pilocytic astrocytoma
Pilocytic astrocytoma is the most common type of brain tumor in pediatric population, generally connected with favorable prognosis, although recurrences or dissemination sometimes are also observed. For tumors originating in supra- or infratentorial location different molecular background was sugges...
ORGANISM(S): Homo sapiens 
2015-10-30 | E-GEOD-73066 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling of fine needle aspiration biopsy of thyroid nodules in Polish patients
With increasing detection of thyroid nodules due to the widespread availability of sonography, and the subjective nature of cytological assessment, molecular evaluation can support physicians in distinguishing benign and malignant nodules. The dataset consists of 20 benign or malignant biopsy sample...
ORGANISM(S): Homo sapiens 
2026-04-15 | E-MTAB-16876 | biostudies-arrayexpress
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