Sort   by:  
 Page size 
TranscriptomicsDefinition and characterization of the systemic T cell dysregulation in untreated indolent B cell lymphoma and very early CLL
Epidemiological data show that the immune system may control or promote emergence and growth of a neoplastic lymphomatous clone. Conversely, systemic lymphomas, especially myeloma and CLL, are associated with clinical immunodeficiency. This prospective controlled study demonstrates substantially red...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-23293 | biostudies-arrayexpress
TranscriptomicsTBI induced intestinal tissue damage
Tissue damage precedes GvHD and the events leading up to this inflammatory disease are not well understood. To identify cell populations that may invade the intestinal tract after total body irradiation (TBI), we performed a microarray based gene expression analysis of the intestinal tract isolated ...
ORGANISM(S): Mus musculus 
2014-04-28 | E-MTAB-1566 | biostudies-arrayexpress
TranscriptomicsNext generation sequencing analysis of microRNAs in brown preadipocytes and in vitro differentiated mature brown fat cells
We performed a genome-wide deep sequencing analysis of the microRNAs abundant in mesenchymal stem cells (MSCs) derived from murine brown adipose tissue and in in vitro differentiated mature brown adipocytes. Several microRNAs were identified as differentially regulated when comparing datasets from M...
ORGANISM(S): Mus musculus 
2013-05-28 | E-GEOD-45499 | biostudies-arrayexpress
TranscriptomicsCD3/CD28 and IL-2 stimulated mouse CD8 T cells with or without anti-CD132 blocking antibody
Mouse CD8 T cells were isolated from total splenocytes from C57BL/6 mice by MACS separation. Cells were incubated for 48 h with CD3/CD28 DynaBeads and 50 ng/ml IL-2 for 48 h with or without 100 nm anti-CD132 blocking antibody. Cells were collected and RNA was isolated.
ORGANISM(S): Mus musculus 
2015-03-23 | E-MTAB-2960 | biostudies-arrayexpress
TranscriptomicsThe transcriptional regulator LysG of Mycobacterium tuberculosis activates lysE in a lysine-dependent manner
To evaluate what genes are under the transcriptional control of LysG(Mt), a whole genome differential gene expression analysis of Wt Mt (Wt_Mtb) and del_ysG(1985c) was done, based on RNA-seq. Both were grown in a minimal medium supplemented with either 5 mM lysine, 10 mM ammonium or 3.34 mM histidin...
ORGANISM(S): Mycobacterium tuberculosis 
2017-09-03 | E-MTAB-6011 | biostudies-arrayexpress
TranscriptomicsAnalysis of mouse T cell transcription profile after co-culture with BaF3 cells with or without the oncogenic point mutation JAK2 V617F
The activation of PD-1 (Programmed Death receptor-1) on T cells can cause T cell exhaustion and immune tolerance. Some tumors up-regulate the expression of the ligand of PD-1, namely PD-L1 (Programmed Death Receptor-Ligand 1), thus preventing anti-tumor immune response and promoting immune-escape. P...
ORGANISM(S): Mus musculus 
2018-12-01 | E-MTAB-5028 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis Col-0 plants with wild type, arr1-1 knock-out, ARR1 over-expressor and ARR1-SRDX fusion protein over-expressor genotypes treated with 6-Benzyladenine for different lengths of time
Arabidopsis thaliana Col-0 plants and three other genotypes (ARR1 overexpressor, arr1-1 knockout, overexpressor of ARR1-SRDX fusion protein) were grown in liquid media (1/2 MS, 1 g/L sucrose, 0.5 g/L MES, pH 5.7) in a Percival AR-66L growth chamber at 24 oC, 16:8 h day:night cycle, and 100 µE light ...
ORGANISM(S): Arabidopsis thaliana 
2008-08-31 | E-MEXP-689 | biostudies-arrayexpress
UnknownPredicting the functional effects of voltage-gated potassium channel missense variants with multi-task learning.
Not available
S-EPMC9250003 | biostudies-literature
UnknownThe classic. Review article: Traffic accidents. 1966.
Not available
S-EPMC3734421 | biostudies-literature
TranscriptomicsDetermination of the transcription start sites of heterologous promoters in Actinoplanes sp. SE50/110 by 5'-end specific transcriptome sequencing
The promoter structure influences binding and clearance of RNA polymerase and therefore substantially influences expression of a gene. A promoter usually consists of a -10 and a -35-region, an extended -10-motif and A+T-rich upstream promoter elements. Most of these elements are optional, whereas th...
ORGANISM(S): Actinoplanes sp. SE50/110 
2019-10-26 | E-MTAB-8433 | biostudies-arrayexpress
Sort   by:  
 Page size