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ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
UnknownCDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia.
Not available
S-EPMC9643439 | biostudies-literature
UnknownHigh CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL.
Not available
S-EPMC11794132 | biostudies-literature
UnknownThe Antioxidant TEMPOL Protects Human Hematopoietic Stem Cells From Culture-Mediated Loss of Functions.
Not available
S-EPMC10552687 | biostudies-literature
TranscriptomicsRNA-seq analyses of OCI-Ly10 cell lines transduced by doxycycline-inducible lentiviral vectors expressing SPI1 WT or mutant proteins
To characterize the functional consequences of mutant or WT binding
ORGANISM(S): Homo sapiens 
2019-05-10 | E-MTAB-7910 | biostudies-arrayexpress
UnknownOrchestration of human multi-lineage hematopoietic cell development by humanized in vivo bone marrow models.
Not available
S-EPMC12012840 | biostudies-literature
TranscriptomicsRNA-seq analyses of murine naïve B-cells transduced by retroviral vectors driving expression of MYD88 L265P and SPI1 (WT or mutant) alone or in combination
To investigate potential oncogenic cooperation of MYD88 and SPI1 mutations on cellular proliferation and B-cell differentiation
ORGANISM(S): Mus musculus 
2019-05-03 | E-MTAB-7882 | biostudies-arrayexpress
UnknownDevelopmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia.
Not available
S-EPMC11414260 | biostudies-literature
UnknownGenetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Not available
S-EPMC3274628 | biostudies-literature
TranscriptomicsFunctional and transcriptional heterogeneity of human hemopoietic lympho-myeloid progenitors
Cord blood (CB) samples from normal donors were obtained with informed consent. Fresh CB samples were processed within 18-34h after collection. Mononuclear cells were isolated and CD34+ fraction was separated. CB CD34+ enriched fraction was lineage depleted by staining with purified anti-human CD2, ...
ORGANISM(S): Homo sapiens 
2017-10-03 | E-MTAB-5456 | biostudies-arrayexpress
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