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ProteomicsProteomics data of GFP::PGL-3 IP-MS compared to GFP control
We carried out immunoprecipitation-mass spectrometry (IP-MS) analysis to identify the protein components of PGL granules in heat-stressed embryos. GFP::PGL-3 proteins were immunoprecipitated from extracts of embryos grown at 26 oC and the interacting proteins were identified by LC-MS/MS. Proteins in...
ORGANISM(S): Caenorhabditis elegans 
2023-04-01 | PXD040246 | Pride
Gfp::pgl-3 Ip-ms C.elegans Pgl granules 
OthereIF4e Assembly into Germ Granules is Essential for its Repressive Function
In metazoans, germ cells play a fundamental role in ensuring the continuity of animal life. Germ cells contain germ granules, cytoplasmic non-membrane bound organelles also referred to as RNA-protein condensates. These germ granules house a variety of RNAs and proteins essential for germline identit...
ORGANISM(S): Caenorhabditis elegans 
2025-06-16 | GSE299469 | GEO
UnknownAutophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans.
Not available
S-EPMC6534287 | biostudies-literature
ProteomicsWAGO-4 Localization to Germ Granules Is Important for Its Accurate Small RNA Loading
There were several MS experiments used in this study: 1) Proximity labeling of the P granules 2) Protein levels estimation from whole worm lysates and 3) wago-4 KO expression check (PRM analysis). 1) Proximity labeling strategy was used to estimate P granule composition in 3xFG mutant (FG domains of...
ORGANISM(S): Caenorhabditis elegans 
2025-10-14 | PXD062557 | Pride
C. elegans Proximity labeling Fg repeats P granules 
UnknownPGL germ granule assembly protein is a base-specific, single-stranded RNase.
Not available
S-EPMC4747772 | biostudies-literature
GenomicseIF4e Assembly into Germ Granules is Essential for its Repressive Function
eIF4e Assembly into Germ Granules is Essential for its Repressive Function
PRJNA1274489 | ENA
UnknownA mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro.
Not available
S-EPMC12107180 | biostudies-literature
UnknownC. elegans germ granules require both assembly and localized regulators for mRNA repression.
Not available
S-EPMC7881195 | biostudies-literature
UnknownProtein-based condensation mechanisms drive the assembly of RNA-rich P granules.
Not available
S-EPMC8238508 | biostudies-literature
UnknownA gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos.
Not available
S-EPMC6668929 | biostudies-literature
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