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MetabolomicsPGM3-Driven Hexosamine Biosynthesis Facilitates Hepatocellular Carcinoma Progression through YBX1 O-GlcNAcylation (Untargeted metabolomics)
Phosphoglucomutase 3 (PGM3) is one of the rate-limiting enzymes in the hexosamine biosynthesis pathway (HBP) and a key regulator of HBP metabolic flux. Despite the functional role of PGM3 has been validated in various tumors, its function and molecular mechanism in hepatocellular carcinoma (HCC) rem...
2026-09-03 | MTBLS15545 | MetaboLights
MetabolomicsButyric acid derived from porcine-derived antioxidant probiotic PGM326 enhances intestinal cell differentiation by promoting oxidative phosphorylation

This study not only identified an efficient host-homologous antioxidant probiotic, PGM326, but also systematically elucidated its mechanism of exerting antioxidant function by synthesizing BA to promote OXPHOS in intestinal epithelial cells, thereby enhancing cell differentiation. This provides a...

2026-02-01 | MTBLS13818 | MetaboLights
TranscriptomicsLuxS/AI-2 quorum sensing microarray comparison in Yersinia pestis at 30°C
The AI-2 quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strain...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30108 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ysp AHL quorum sensing at 37°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30328 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ysp AHL quorum sensing at 30°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30329 | biostudies-arrayexpress
ProteomicsDay-night phosphoproteome analysis in WT, pgm mutant and sweet11/sweet12 mutant
In this progect, we anallyzed the phosphoproteome change of shoot and root from WT pgm mutant and sweet11/sweet12 mutant at the end of day and the end of night. The purpose is to understand the role of sugar distribution in shoot and root phopshoproteome.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-12 | PXD031942 | Pride
End of day Pgm End of night Sweet1/sweet12 Membrane fraction Arabidopsis shoot/root 
TranscriptomicsExtracellular Vesicles in Luminal Fluid of the Ovine Uterus
Exosomes/microvesicles (hereafter referred to as extracellular vesicles) were isolated from the ULF of day 14 cyclic and pregnant ewes using ExoQuick-TC. Extracellular vesicle RNA was pooled (n=4 per status) and analyzed for small RNAs by sequencing on the Ion Torrent PGM platform and analysis with ...
ORGANISM(S): Ovis aries 
2014-01-11 | E-GEOD-53974 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of quorum sensing null strain in Yersinia pestis CO92 at 30°C
Yersinia pestis is the etiology of plague that is able to sense cell density by quorum sensing. The function of quorum sensing in Y.pestis is not clear. Here, the process of quorum sensing was investigated by comparing transcript profiles when three quorum sensing synthase genes are knocked out. Two...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-20217 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of ypeIR mutation in Yersinia pestis at 37°C
The etiologic agent of bubonic plague, Yersinia pestis, senses cell density-dependent chemical signals to synchronize transcription between cells of the population in a process named quorum sensing. Though the closely related enteric pathogen Y. pseudotuberculosis uses quorum sensing system to regul...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30341 | biostudies-arrayexpress
GenomicsBarbonymus schwanenfeldii Ion Torrent PGM
Barbonymus schwanenfeldii genome sequencing on Ion Torrent PGM 400bp 316v2 chip
PRJEB5854 | ENA
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