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MetabolomicsDynamic utilization of low-molecular-weight organic substrates across a microbial growth rate gradient

AIM: Low-molecular-weight organic substances (LMWOSs) are at the nexus between micro-organisms, plant roots, detritus and the soil mineral matrix. The nominal oxidation state of carbon (NOSC) has been suggested as a potential parameter for modelling microbial uptake rates of LMWO...

2023-08-14 | MTBLS3558 | MetaboLights
MetabolomicsLysine acetyltransferase Rv0998 coordinates transcriptional and metabolic adaptation of Mycobacterium tuberculosis to acidic pH

Mycobacterium tuberculosis (Mtb) survives host defences by adapting to host conditions, including acid stress, during infection. A critical survival strategy involves pH homeostasis, mediated by complex signalling systems that regulate metabolic reprogramming and stress responses. While ...

2026-09-03 | MTBLS15171 | MetaboLights
MetabolomicsResponse Mechanisms of Hepatopancreatic Metabolism and Gut Microbiota in Chinese Mitten Crab (Eriocheir sinensis) Under Chronic High-pH Stress

This study subjected Eriocheir sinensis to chronic high-pH stress (control: pH=8; experimental groups: pH=9 and pH=10) and integrated hepatopancreas transcriptomic/metabolomic analyses with intestinal microbiota 16S rRNA sequencing to explore its adaptive mechanisms. The results revealed distinct...

2026-07-04 | MTBLS13708 | MetaboLights
MetabolomicsA Divergent Selection on Breast Meat Ultimate pH, a Key Factor for Chicken Meat Quality, is Associated With Different Circulating Lipid Profiles

BACKGROUND: Chicken meat has become a major source of protein for human consumption. However, the quality of the meat is not yet under control, especially since pH values that are too low or too high are often observed. In an attempt to get a better understanding of the genetic a...

2022-06-01 | MTBLS2970 | MetaboLights
ModelsAl-Husari2013 - pH and lactate in tumor
The paper describes a model of pH control in tumor. Created by COPASI 4.26 (Build 213) This model is described in the article: Regulation of tumour intracellular pH: A mathematical model examining the interplay between H and lactate Maymona Al-Husari, Steven D. Webb Journal of Theoretical Biolog...
2024-09-02 | BIOMD0000000805 | BioModels
GenomicspH gradient in a sub-tropical soil (ABC, Tibagi, Brazil)
16S rRNA sequencing of a sub-tropical soil pH gradient
PRJNA413794 | ENA
TranscriptomicsTranscription profiling of E. coli K12 W3110 cultured in three different steady-state external pH conditions
Gene expression profiles of Escherichia coli K-12 W3110 were compared as a function of steady-state external pH. Cultures were grown with aeration to an optical density at 600 nm of 0.3 in potassium-modified Luria-Bertani medium buffered at pH 5.0, 7.0, and 8.7. For each of the three pH conditions, ...
ORGANISM(S): Escherichia coli K12 
2007-09-21 | E-GEOD-4511 | biostudies-arrayexpress
GenomicsIntertidal epilithic bacteria diversity changes along a naturally occurring pH gradient.
16SrRNA gene microbial community profiling about a naturally occuring pH gradient.
PRJEB5298 | ENA
GenomicsMetagenomic survey of viruses and prokaryotes in Chinese paddy soils along a pH gradient
Metagenomic survey of viruses and prokaryotes in Chinese paddy soils along a pH gradient Raw sequence reads
PRJNA1338357 | ENA
ProteomicsSCX_MS raw files and RP_MS raw files
A novel one-dimensional on-line pH gradient-eluted strong cation exchange (SCX)-nano-ESI-MS/MS method was developed for protein identification and tested with mixture of six standard proteins, total lysate of HuH7 and N2a cells, as well as membrane fraction of N2a cells. This method utilized an on-l...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2016-01-28 | PXD003438 | Pride
Strong cation exchange Ph gradient 
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